Hydrocodone vs. oxycodone: Liphapang, ho tšoana, 'me ke hofe ho u loketseng
Lithethefatsi Vs. MotsoalleKakaretso ea lithethefatsi le liphapang tse kholo | Maemo a phekotsoe | Tshebetso | Ho koahela inshorense le papiso ea litšenyehelo | Litla-morao | Likamano tsa lithethefatsi | Litemoso | LBH
Hydrocodone le oxycodone li peli opioid Litlhare tse fanoang ke ngaka li bontšoa kalafo ea bohloko bo mahareng ho isa ho bo tebileng, hangata bakeng sa bohloko bo bohloko. Lithethefatsi tsena ka bobeli li khetholloa e le lithethefatsi, ho bolelang hore lia lemalla ebile li na le monyetla o moholo oa tlhekefetso. Lithethefatsi tsena ka bobeli li sebetsa ka ho tlama li amohelang bohloko, tse bitsoang li-mu receptors, bokong, tse fokolisang kapa tse thibelang matšoao a bohloko, mme li felle ka phomolo ea bohloko. Hobane lithethefatsi ka bobeli li matla haholo, hangata li sebelisoa kamora 'opereishene, kapa maemong ao ho felisang bohloko bo bohloko bo ke keng ba atleha kapa bo ke keng ba mamelloa.
Phapang e kholo ke efe lipakeng tsa hydrocodone le oxycodone?
Ho na le mefuta e mengata e fapaneng ea hydrocodone le oxycodone. Lithethefatsi tsena ka bobeli ke meriana ea bohloko ba Lenaneo la II; hona ho bolela hore setlhare se ka ba le monyetla o moholo oa tlhekefetso.
Hydrocodone (Hydrocodone coupons | Hydrocodone ke eng?) E fumanehang hangata e le mabitso a lebitso la Norco kapa Vicodin, a nang le hydrocodone hammoho le Tylenol (acetaminophen, e atisang ho khutsufatsoa joaloka APAP). Hydrocodone / APAP e ka fumanoa ka foromo ea pilisi hammoho le foromo ea metsi. Hydrocodone e ka fumanoa e kopane le ibuprofen, le meriana e kopaneng ea ho khohlela, joalo ka sirapo ea Hycodan kapa matlapa (hydrocodone / homatropine) kapa ho emisoa ha Tussionex (hydrocodone / chlorpheniramine). U le mong, hydrocodone e ka fumanoa litlhare tse lokolloang tse ngata Zohydro ER (ext-release) kapa Hysingla ER.
Oxycodone (Oxycodone coupons | Oxycodone ke eng?) E tloaetsoeng ho beoa e le mong, joalo ka generic bakeng sa OxyIR (ho lokolloa hanghang). E fumaneha hape e le 'ngoe ka sethethefatsi sa nako e telele se bitsoang OxyContin. Oxycodone e boetse e fumaneha hangata e kopane, joalo ka Percocet, e nang le oxycodone le APAP.
Lithethefatsi tsena ka bobeli li fapana ka litekanyo ho latela lilemo le boemo 'me ka kakaretso li laeloa ka tekanyetso e tlase ka ho fetesisa ka nako e khuts'oane ka ho fetisisa. Linaha tsohle li na le melao mabapi le litaelo tsa opioid, ka lebaka la matla a tsona a matla a tlhekefetso.
Phapang e kholo lipakeng tsa hydrocodone le oxycodone | ||
---|---|---|
Hydrocodone | Oxycodone | |
Sehlopha sa lithethefatsi | Opiate (narcotic) bohloko bo hlabang | Opiate (narcotic) bohloko bo hlabang |
Boemo ba cha / cha | Cha le generic | Cha le generic |
Lebitso la generic ke mang? Lebitso la lebitso ke mang? | E tloaelehileng: hydrocodone, hydrocodone / APAP, jj. Moetso: Zohydro ER, Hysingla ER Moetso: o kopane le APAP: Norco, Lortab, Vicodin | E tloaelehileng: oxycodone, oxycodone / APAP, jj. Moetso: OxyIR, OxyContin Moetso: o kopane le APAP: Percocet |
Sethethefatsi se kena ka mefuta e fe? | Letlapa, letlapa le lokolloang nako e telele, sirapo e le setlhare se kopaneng | Letlapa, letlapa le lokolloang nako e telele, tharollo ea molomo |
Tekanyo e tloaelehileng ke efe? | Mohlala: Hydrocodone / APAP 5/325 mg: Letlapa (li) tse 1-2 lihora tse ling le tse ling tse 4 ho isa ho tse 6 ha ho hlokahala bakeng sa bohloko (boholo ba matlapa a 8 ka letsatsi) | Mohlala: Letlapa le lokolloang hanghang: 5 ho isa ho 15 mg lihora tse 4 ho isa ho tse 6 kamoo ho hlokahalang OxyContin: 20 mg lihora tse ling le tse ling tse 12 |
Kalafo e tloaelehileng e nka nako e kae? | Nako e khuts'oane, e ka sebelisoa nako e teletsana ho ipapisitsoe le boemo ba kalafo (joalo ka bohloko bo sa foleng) le karabelo | Nako e khuts'oane, e ka sebelisoa nako e teletsana ho ipapisitsoe le boemo ba kalafo (joalo ka bohloko bo sa foleng) le karabelo |
Ke mang ea sebelisang meriana eo? | Batho ba baholo | Batho ba baholo |
Maemo a alafiloeng ke hydrocodone le oxycodone
Hydrocodone le oxycodone ka bobeli li bontšitsoe bakeng sa taolo ya bohloko e matla hoo e ka hlokang opioid, moo mekhoa e meng ea kalafo (e seng li-opioid) e sa lekanang kapa e mamelloang
Boemo | Hydrocodone | Oxycodone |
Tsamaiso ea bohloko bo tebileng ho lekana ho hloka analio ea opioid le hore na ke mekhoa efe e meng ea kalafo e sa lekanang | Ho joalo | Ho joalo |
Na hydrocodone kapa oxycodone e sebetsa hantle?
E laoloang ka sefofu se habeli ho ithuta ea hydrocodone vs oxycodone sebakeng sa maemo a tšohanyetso, phomolo ea bohloko e ne e ts'oana, ka metsotso e 30 le metsotso e 60 bakeng sa hydrocodone kapa oxycodone ka bobeli. Lithethefatsi tsena ka bobeli li bile le litla-morao tse tšoanang, ha hydrocodone e baka ho sokela hanyane ho feta oxycodone.
E 'ngoe ho ithuta e bonts'itse hydrocodone / APAP le oxycodone / APAP ho ba le litlamorao tse ts'oanang le phokotso ea bohloko, empa oxycodone / APAP e ne e le matla ka makhetlo a 1.5 ho feta hydrocodone / APAP.
Bobeli hydrocodone le oxycodone ke lipilisi tse matla tse nang le monyetla o moholo oa tlhekefetso, tse sebelisoang ha lipilisi tse mahlonoko li sa fana ka phomolo e sebetsang ea bohloko, kapa li ke ke tsa mamelloa. Meriana e sebetsang ka ho fetisisa e lokela ho khethoa ke ngaka ea hau, e tla sheba setšoantšo sohle sa maemo a hau a bophelo, nalane le meriana e meng eo u e nkang.
Ho bapisa le ho bapisa litšenyehelo tsa hydrocodone vs oxycodone
Ka lebaka la melao e fapaneng ea mmuso, haeba o fumana opioid ka lekhetlo la pele, ho ka etsahala hore o tla fumana e nyane.
Kemiso e tloaelehileng ea matlapa a 20 a hydrocodone-acetaminophen e ka bitsa chelete e fetang $ 100. Ka setlankane sa SingleCare, Vicodin kapa Norco ea generic e ka tsamaisa $ 26- $ 41. Kemiso e tloaelehileng ea matlapa a oxycodone-acetaminophen ke $ 25- $ 50. Theko ea kantle ho pokotho ke $ 10- $ 15 ka setlankane sa SingleCare.
Fumana karete ea theolelo e tsoang ho SingleCare
Hydrocodone | Oxycodone | |
E koahetsoe ka inshorense? | Ho joalo | Ho joalo |
E koahetsoe ka tloaelo ke Medicare Part D? | Ho joalo | Ho joalo |
Tekanyo e tloaelehileng | # 20, lipilisi tsa hydrocodone / APAP 5/325 mg | # 20, lipilisi tsa oxycodone / APAP 5/325 mg |
Mofuta o tloaelehileng oa Medicare Part D | $ 3-73 | $ 3-90 |
Litsenyehelo tsa SingleCare | $ 26- $ 41 | $ 10- $ 15 |
Litla-morao tse tloaelehileng tsa hydrocodone vs oxycodone
Litla-morao tse tloaelehileng tsa hydrocodone ke hlooho e bobebe, ho tsekela, sedation, ho nyekeloa ke pelo le ho hlatsa. Litla-morao tse ling li ka kenyelletsa ho sokela, ho tšoenyeha, ho phatloha ha letlalo, ho tepella le ho itšetleha.
Litla-morao tse tloaelehileng tsa oxycodone ke ho nyekeloa ke pelo, ho sokela, ho hlatsa, ho opeloa ke hlooho, ho hlohlona, ho hlobaela, ho tsekela, bofokoli le ho otsela. Litla-morao tse ling li ka kenyelletsa ho otlanya pelo, ho omella molomo, ho tšoenyeha, ho phatloha ha letlalo le ho itšetleha.
Litla-morao tse ling li ka hlaha. Ikopanye le mofani oa tlhokomelo ea bophelo bakeng sa tlhaiso-leseling e batsi mabapi le litlamorao.
Likamano tsa lithethefatsi tsa hydrocodone vs oxycodone
Ho nka hydrocodone kapa oxycodone ka meriana e itseng e kopantsoeng ke enzyme e bitsoang CYP3A4 kapa CYP2D6 ho ka baka tšebelisano 'moho ea lithethefatsi. Lithethefatsi tsena li tsejoa e le li-enzyme inhibitors 'me li kenyelletsa lithibela-mafu tsa macrolide, li-antifungal tsa azole le li-protease inhibitors. Ho li sebelisa hammoho le hydrocodone kapa oxycodone ho ka baka maemo a phahameng a opioid, e ka bang kotsi haholo.
Lithethefatsi tse ling, tse tsejoang e le li-inducers, li na le litlamorao tse fapaneng, li theola boemo ba opioid hore bo se sebetse kapa bo ka baka matšoao a ho hula.
Ho sebelisa li-benzodiazepines kapa li-depressing tse ling tsa CNS (ho kenyeletsoa le litlhare tse ling tsa opioid) hammoho le hydrocodone kapa oxycodone ho ka lebisa ho hypotension, khatello ea maikutlo ea ho hema, sedation e tebileng, coma le lefu.
Ho nka hydrocodone kapa oxycodone ka lithethefatsi tse eketsang serotonin ho ka eketsa kotsi ea lefu la serotonin. Lithethefatsi tsena li kenyelletsa li-anti-depressing tsa SSRI le SNRI, lithibela-mafu tsa tricyclic, mesifa e khathollang, MAO inhibitors (MAO inhibitors ha ea lokela ho sebelisoa nakong ea matsatsi a 14 a hydrocodone kapa oxycodone), le li-triptan tsa migraine. Ikopanye le mofani oa tlhokomelo ea bophelo bakeng sa lenane le felletseng la litšebelisano tsa lithethefatsi.
Lithethefatsi | Sehlopha sa Lithethefatsi | Hydrocodone | Oxycodone |
Erythromycin Biaxin (clarithromycin) | Macrolide lithibela-mafu | Ho joalo | Ho joalo |
Diflucan (fluconazole) Nizoral (ketoconazole) | Li-antifungal tsa Azole | Ho joalo | Ho joalo |
Norvir (ritonavir) | Protease inhibitors | Ho joalo | Ho joalo |
Rifampin Tegretol (carbamazepine) Dilantin (phenytoin) | Li-inducers tsa CYP3A4 | Ho joalo | Ho joalo |
Xanax (alprazolam) Valium (diazepam) Ativan (lorazepam) Klonopin (clonazepam) | Benzodiazepines | Ho joalo | Ho joalo |
Methadone Tylenol e nang le codeine (APAP / codeine) Duragesic (fentanyl) Morphine Mefuta efe kapa efe ea hydrocodone kapa oxycodone | Li-opioids | Ho joalo | Ho joalo |
Joala | Joala | Ho joalo | Ho joalo |
Flexeril (cyclobenzaprine) Skelaxin (metaxalone) | Phomolo ea mesifa | Ho joalo | Ho joalo |
Imitrex (sumatriptan) Maxalt (rizatriptan) | Litlhapi | Ho joalo | Ho joalo |
Prozac (fluoxetine) Paxil (paroxetine) Zoloft (sertraline) Selexa (citalopram) Lexapro (escitalopram) | Li-anti-depressing tsa SSRI | Ho joalo | Ho joalo |
Pamelor (nortriptyline) Elavil (ts'ebetsong) | Tricyclic ho imeloa kelellong | Ho joalo | Ho joalo |
Cymbalta (duloxetine) Effexor (venlafaxine) Pristiq (desvenlafaxine) | SNRI ho imeloa kelellong | Ho joalo | Ho joalo |
Hydrochlorothiazide Lasix (furosemide) | Li-diuretics | Ho joalo | Ho joalo |
Azilect (rasagiline) Moholo (selegiline) Parnate (tranylcypromine) | MAO inhibitors | Ho joalo | Ho joalo |
Cogentin (benztropine) Benadryl (diphenhydramine) Ditropan (oxybutynin) Tlosa (tolterodine) | Lithethefatsi tsa anticholinergic | Ho joalo | Ho joalo |
Litemoso tsa hydrocodone le oxycodone
Ho na le temoso ea mabokose ho hydrocodone le oxycodone, e leng temoso e matla ka ho fetesisa e hlokoang ke FDA. Litemoso tse ling li kenyelletsa:
- Li-opioid li na le kotsi ea ho lemalla lithethefatsi, ho hlekefetsoa le ho sebelisoa hampe, tse ka lebisang ho feteletseng le lefung. Bakuli ba lokela ho hlahlojoa hore na ba na le kotsi pele ba nka opioid mme ba lokela ho beoa leihlo khafetsa.
- Ho etsa bonnete ba hore melemo ea li-opioid e feta kotsi ea bokhoba ba tahi, ts'ebeliso e mpe ea lithethefatsi le ts'ebeliso e mpe, lik'hamphani tsa lithethefatsi li tlameha ho ruta bafani ba tlhokomelo ea bophelo. Bafani ba tlhokomelo ea bophelo bo botle ba tlameha ho tlatsa lenaneo la REMS (Risk Evaluation and Mitigation Strategy) le lumellanang, ba ele hloko ka botlalo bakuli le bahlokomeli ka lengolo le leng le le leng la bongaka, 'me ba hatise bohlokoa ba ho bala tataiso ea meriana, e fuoang lengolo le leng le le leng la ngaka.
- Li-opioid li ka baka khatello ea maikutlo e tebileng, e sokelang bophelo kapa e bolaeang. Bakuli ba lokela ho beoa leihlo, haholo-holo qalong ea kalafo le ho latela phetoho ea litekanyetso.
- Ho noa ka phoso, haholo-holo ke bana, ho ka fella ka ho feta tekano ho bolaeang. Bakuli ba lokela ho laeloa ho boloka li-opioid moo bana ba ke keng ba li fihlela.
- Leonatal opioid Retreat syndrome e ka baka ts'ebeliso ea opioid nako e telele nakong ea bokhachane mme e ka beha bophelo kotsing haeba e sa tsejoe le ho phekoloa.
- Ho sebelisa li-opioid ka meriana e meng e kopantsoeng ke enzyme cytochrome P 450 3A4 e ka eketsa maemo a opioid mme ea baka litlamorao tse eketsehileng le khatello ea maikutlo e ka bang bolaeang ea phefumoloho.
- Ho sebelisa lithethefatsi tsa benzodiazepine tse kang Xanax (alprazolam), Valium (diazepam), kapa li-depressing tse ling tsa CNS, joalo ka li-opioid tse ling (kapa joala), ho ka baka ho hlonama ho tebileng, khatello ea maikutlo, ho akheha le lefu, mme ho lokela ho qojoe ha ho khonahala. Bakuli ba nkang motsoako ona ka lebaka la mekhoa e meng e sa sebetseng ba tlameha ho beoa leihlo leihlo.
Litemoso tse ling le li-contraindication li kenyelletsa:
- Hydrocodone kapa oxycodone ha ea lokela ho sebelisoa ho bakuli ba nang le khatello ea maikutlo e matla ea ho hema, asthma e matla kapa e matla ea bronchial maemong a sa shejoeng, tšitiso ea mala, kapa hypersensitivity ho eng kapa eng ea lisebelisoa.
- Hydrocodone kapa oxycodone ha ea lokela ho sebelisoa ho bakuli ba nang le lefu le sa foleng la pulmonary kapa bakuli ba holileng kapa ba fokolang.
- Ho haella ha adrenal ho ka hlaha, hangata kamora khoeli e le 'ngoe. Batla kalafo haeba ho na le a mang a matšoao ana a hlahang: ho nyekeloa ke pelo, ho hlatsa, ho ipolaisa tlala, mokhathala, bofokoli, ho tsekela, le khatello e tlase ea mali.
- Hydrocodone kapa oxycodone e ka baka khatello e matla ea mali.
- Se ke oa sebelisa hydrocodone kapa oxycodone ho bakuli ba nang le bokooa ba kelello kapa ba akhehileng.
- Hydrocodone kapa oxycodone e ka eketsa menyetla ea ho oela ho bakuli ba nang le mathata a ho ts'oaroa.
- Hydrocodone kapa oxycodone ha ea lokela ho tlosoa ka tšohanyetso empa e lokela ho thelisoa butle.
- Se ke oa khanna kapa ua sebelisa mechini ho fihlela u tseba hore na moriana oo ama joang.
- Li-opioid tse sa sireletsoeng li ka ba kotsi ho mang kapa mang ka lapeng, ho kenyeletsoa le baeti. Boloka ka mokhoa o sireletsehileng, moo bana ba sa boneng le moo ba ka fihlelloang, le sebakeng se sa fihleloeng ke ba bang. Botsa setsebi sa hau sa tlhokomelo ea bophelo hore na u ka lahla li-opioid tse sa sebelisoang joang sebakeng sa heno.
Hobane ha ho na lithuto tse laoloang hantle ho basali, hydrocodone kapa oxycodone ha ea lokela ho sebelisoa nakong ea bokhachane ntle le haeba melemo e feta likotsi. Ts'ebeliso ea nako e telele ea li-opioid nakong ea bokhachane, ekaba ts'ebeliso ea bongaka kapa e sa sebeliseng bongaka, e ka baka ts'epahalo ea 'mele ho lesea, e lebisang ho neonatal opioid khaotsa ho kula nakoana kamora ho hlaha.
Litemoso tse ikhethang ho acetaminophen (APAP) eo hangata e fumanoang hammoho le hydrocodone kapa oxycodone ke:
- Acetaminophen e ka baka tšabo e mpe ea letlalo joalo ka pustulosis e matla e akaretsang e akaretsang (AGEP), Stevens-Johnson Syndrome (SJS), le chefo ea epidermal necrolysis (TEN), e ka bolaeang. Bakuli ba lokela ho batla kalafo e potlakileng haeba karabelo ea letlalo e hlaha.
- Ho na le kotsi ea ho hloleha ha sebete ka lebaka la APAP. Ngaka ea hau e lokela ho u joetsa tekanyo e phahameng ea letsatsi le letsatsi ea APAP eo u ka e nkang, 'me u lokela ho hlahloba meriana e meng eo u e nkang bakeng sa APAP (joalo ka NyQuil).
- Hypersensitivity kapa anaphylaxis e ka hlaha. Batla kalafo ea tšohanyetso haeba ho ka ba le matšoao le matšoao ana: ho ruruha ha sefahleho, molomo le 'metso, khatello ea phefumoloho, urticaria, lekhopho, pruritus le ho hlatsa.
Lipotso tse botsoang khafetsa mabapi le hydrocodone vs. oxycodone
Hydrocodone ke eng?
Hydrocodone ke painkiller ea opioid e sebelisetsoang ho phekola bohloko bo sa arabeleng lipilisi tse bohloko tse bohloko. E fumaneha ka mefuta e fapaneng, hangata e nang le acetaminophen ka sebopeho sa Norco.
Oxycodone ke eng?
Oxycodone ke moriana o kokobetsang bohloko oa opioid o sebelisetsoang ho phekola bohloko bo sa arabeleng lipilisi tse bohloko tse bohloko. E fumaneha ka mefuta e fapaneng, hangata ka bo eona (ka mefuta ea ho lokolla hanghang le e atolositsoeng) hape hangata le acetaminophen ka sebopeho sa Percocet.
Na hydrocodone le oxycodone lia tšoana?
Lithethefatsi tsena ka bobeli ke li-analgesics tse matla tsa opioid. Le ha li ts'oana haholo, li na le liphapang tse ling, joalo ka tekanyetso, e boletsoeng kaholimo.
Na hydrocodone kapa oxycodone e betere?
Liphuputsong, lithethefatsi tsena ka bobeli li bonts'itse ho fana ka phomolo e sebetsang ea bohloko. Leha ho le joalo, lithethefatsi tsena ka bobeli li matla haholo ka monyetla o moholo oa tlhekefetso. Ikopanye le mofani oa tlhokomelo ea bophelo bakeng sa likeletso tse ikhethileng.
Na nka sebelisa hydrocodone kapa oxycodone ha ke le moimana?
Ha ua lokela ho sebelisa hydrocodone kapa oxycodone ha u le moimana ntle le haeba ngaka ea hau e bona hore molemo oa hau o feta kotsi ea lesea. Hape, ho sebelisa li-opioid nako e telele haholo nakong ea bokhachane ho ka baka ts'episo ho lesea, mme ho ka lebisa ho lefu la ho tsoala opioid la neonatal.
A na nka sebelisa hydrocodone kapa oxycodone ka joala?
Che. Hydrocodone kapa oxycodone ha ea lokela ho sebelisoa le joala. Motsoako ona o ka lebisa ho sedation e tebileng, khatello ea maikutlo, ho akheha kapa lefu.
Na le ka nka hydrocodone le oxycodone hammoho?
Che. Hydrocodone le oxycodone ha lia lokela ho sebelisoa hammoho. Motsoako ona o ka ba kotsi haholo 'me oa baka khatello ea maikutlo kapa lefu. Lena ke le leng la mabaka a hobaneng ho le bohlokoa ho lahla li-opioid tsa khale ha li se li sa hlokahale. Botsa rakhemisi oa hau hore na a ka lahla meriana joang haufi le uena.
Hobaneng ha batho ba bang ba sebelisa hydrocodone bakeng sa boithabiso?
Ha a ntse a fokotsa bohloko, li-opioid tse kang hydrocodone kapa oxycodone le tsona li ka hlahisa mofuta oa phello ea nyakallo . Li-opioid li na le monyetla o moholo oa ts'ebeliso e mpe ea lithethefatsi. Ha u noa moriana oa opioid, sebelisa feela kamoo u laetsoeng kateng. Se ke oa noa litekanyetso tse ling hape o se ke oa kopanya le joala. Botsa ngaka ea hau kapa setsebi sa meriana ka litšebelisano tsa lithethefatsi. Lahla meriana ha u se u sa e hloke; se ke oa e boloka ka nako e 'ngoe. E ka ba kotsi ho mang kapa mang ka lapeng.