Levalbuterol vs Albuterol: Liphapang, ho tšoana, 'me ke hofe ho u loketseng
Lithethefatsi Vs. MotsoalleKakaretso ea lithethefatsi le liphapang tse kholo | Maemo a phekotsoe | Tshebetso | Ho koahela inshorense le papiso ea litšenyehelo | Litla-morao | Likamano tsa lithethefatsi | Litemoso | LBH
Levalbuterol le albuterol ke lithethefatsi tse peli tse sebelisoang ho phekola bronchospasm e amanang le asthma le boloetse bo sa foleng ba pulmonary pulmonary (COPD). Asma ke lefu la ho hema le amang batho ba lilemo tsohle. E tšoauoa ka ho hema, ho khohlela, phefumoloho e khuts'oane le ho thatafala ha sefuba. Ho hakanngoa hore asma e ama batho ba ka bang limilione tse 24 United States, ho kenyeletsoa le bana ba limilione tse 7.
COPD , eo ka linako tse ling e bitsoang emphysema, e na le litšobotsi tse tšoanang le asthma, empa e boetse e kenyelletsa tlhahiso ea mamina a teteaneng moeeng. Lebaka le tobileng la asthma ha le tsejoe, empa bakuli ba bangata ba hlahisang COPD ba na le nalane ea ho tsuba kapa ho pepesetsoa nako e telele le lisosa tsa matšoafo.
Bronchospasm e hlalosa ts'ebetso e hlahang asthma le COPD moo likonteraka tsa sefofane li etsang hore ho be thata ho fetisa moea. Ka linako tse ling sena se bitsoa bronchoconstriction. Levalbuterol le albuterol ka bobeli ba phekola bronchospasm, empa ba sebetsa ka tsela e fapaneng.
Phapang e kholo lipakeng tsa Levalbuterol le Albuterol ke efe?
Levalbuterol ke sethethefatsi sa ngaka se khethang ka mokhoa o itekanetseng, beta-2-receptor agonist (SABA). Levalbuterol ke R-enantiomer e sebetsang haholo ea motsoako oa li-albuterol. Levalbuterol e hlasimolla li-beta receptors tse hlahisang boikhathollo ba mesifa e boreleli le ea tracheal le tsela e bulehileng haholoanyane. Levalbuterol e fumaneha e le metered-dose inhaler (MDI) e fanang ka 45 mcg dose ka ts'ebetso. E fumaneha hape e le tharollo e tla sebelisoa mochineng oa nebulizer. Tharollo ena ea nebulizer e fumaneha ka bongata ba 0,31 mg / 3 ml, 0.63 mg / 3 ml le 1.25 mg / 3ml.
Albuterol ke sethethefatsi se tlamang se khethang ka mokhoa o itekanetseng, beta-2-receptor agonist (SABA). Albuterol ke motsoako oa khethollo ea morabe oa R-enantiomers le S-enantiomers ha R-enantiomer e le sona sehlahlo se sebetsang haholo le sesebelisoa se sebetsang sa levalbuterol. Racemic albuterol e fumaneha matlapeng a molomo ka matla a ho lokolla hanghang 2 mg le 4 mg le ho lokolloa ha 4 mg le 8 mg. Albuterol e boetse e fumaneha ka tharollo ea molomo ka 2 mg / 5 ml. Albuterol e boetse e na le inhaler ea methapo e fanang ka 90 mcg ka ts'ebetso le mefuta e fapaneng ea tharollo ea nebulizer.
| Liphapang tse kholo lipakeng tsa Levalbuterol le Albuterol | ||
|---|---|---|
| Levalbuterol | Albuterol | |
| Sehlopha sa lithethefatsi | Beta-2-agonist e sebetsang ka nakoana | Beta-2-agonist e sebetsang ka nakoana |
| Boemo ba cha / cha | Brand le generic lia fumaneha | Brand le generic lia fumaneha |
| Lebitso la lebitso ke mang? | Xopenex | ProAir, Proventil, Ventolin, Accuneb, Vospire |
| Sethethefatsi se kena ka mefuta e fe? | Inhaler ea tekanyo ea methapo, tharollo ea nebulizer | Inhaler ea tekanyo ea methapo, tharollo ea nebulizer, matlapa a molomo, tharollo ea molomo |
| Tekanyo e tloaelehileng ke efe? | 0.63 mg ka nebulizer kapa 45 mcg ka MDI lihora tse ling le tse ling tse 4-6 | 2.5 mg ka nebulizer kapa 90 mcg ka MDI lihora tse ling le tse ling tse 4-6 |
| Kalafo e tloaelehileng e nka nako e kae? | Nako e khuts'oane, e khuts'oane | Bohare, nakoana e khutšoane |
| Ke mang ea sebelisang meriana eo? | Bana ba lilemo li 4 le ho feta, batho ba baholo | Masea, bana, batho ba baholo |
Maemo a phekoloang ke Levalbuterol le Albuterol
Levalbuterol le albuterol ka bobeli li sebetsa ka ho hlohlelletsa li-beta receptors ho baka ho phomola ha mesifa e boreleli moeeng, ka tsela eo e lumella meea ea moea ho bula le ho tsamaisa moea o mongata matšoafong ntle le khanyetso e nyane.
Bobeli ba levalbuterol le albuterol ke tumello ea FDA kalafong ea ho mpefala ha asthma, bronchospasms ea nakoana kapa ho hema, le bronchospasm e amanang le COPD. Ho bohlokoa ho hlokomela hore ha ho lithethefatsi tse lumelloang e le prophylaxis, kapa thibelo, bakeng sa matšoao ana. Leha ho le joalo, albuterol e lumelloa hore e sebelisoe molemong oa thibelo ea bronchospasm e bakoang ke boikoetliso. Ka tloaelo, albuterol e ne e tla fuoa metsotso e 15 pele ho boikoetliso bo lebelletsoeng ho fokotsa menyetla ea bronchospasm e bakoang ke boikoetliso. Levalbuterol ka linako tse ling e sebelisoa e le sieo bakeng sa sesupo sena hape. Off-label ho bolela hore moriana ha oa lumelloa ho sebelisoa pontšong ena ke Tsamaiso ea Lijo le Lithethefatsi (FDA).
Chate e latelang e thathamisa ts'ebeliso e tsebahalang haholo bakeng sa lithethefatsi tsena. Ke mofani oa tlhokomelo ea bophelo feela ea ka bonang hore na litlhare tsena li loketse boemo ba hau. Maemong a asthma e matla le COPD bronchospasm, ka kopo batla kalafo lefapheng le haufi la maemo a tšohanyetso.
| Boemo | Levalbuterol | Albuterol |
| Ho mpefala ha asma | Ho joalo | Ho joalo |
| Nakoana ea bronchospasm / episodic wheezing | Ho joalo | Ho joalo |
| Bronchospasm prophylaxis e bakoang ke ho ikoetlisa | Off-label | Ho joalo |
| COPD bronchospasm e amanang | Ho joalo | Ho joalo |
| Kalafo e matla ea hyperkalemia | Off-label | Off-label |
| Kalafo e tlamang ho mafu a phefumolohang a neonatal | Che | Off-label |
Na Levalbuterol kapa Albuterol e sebetsa hantle?
Levalbuterol le albuterol li bapisoa haholo mabapi le sephetho le asthma le COPD. Selemo sa 2015 ho ithuta batho ba baholo ba hlahlobiloeng ba ileng ba kena sepetlele ba nang le asthma kapa ho mpefala ha COPD ba ileng ba phekoloa ka levalbuterol kapa albuterol e tsamaisoang ke nebulization. Liphetho tsa teko ena ea bongaka li fumane hore liphetho tsa bongaka li ne li ts'oana lipakeng tsa lithethefatsi tsena tse peli mme ka bobeli li ne li sebetsa hantle ho theoleng matšoao a bronchospasm. Leha ho le joalo, theko ea kalafo ea levalbuterol e ne e le theko e phahameng haholo ho feta theko ea kalafo ea albuterol, mme bakuli ba sehlopha sa levalbuterol ba ile ba kena sepetlele nako e telele ho feta bakuli ba sehlopha sa albuterol. Ho lula sepetlele nako e telele ho boetse ho eketsa litjeo tsa kakaretso tsa lits'ebetso.
HO tlhahlobo ea meta le tlhahlobo e hlophisitsoeng tsa liteko tse fapaneng tse supileng, ho kenyeletsoa bakuli ba fetang 1,600, li entsoe ho bapisoa levalbuterol le albuterol ka asthma e matla. Phuputso ena ha ea ka ea fumana phapang e kholo lipakeng tsa lithethefatsi ha e bapisoa le sephetho sa kliniki joalo ka sekhahla sa ho hema, ho tlala ha oksijene le phetoho ea bophahamo ba matšoafo. Ka linako tse ling bophahamo ba matšoafo bo bitsoa bophahamo bo qobelloang ba ho phefumoloha, kapa FEV1, libukeng tsa bongaka. Phuputso ena e phethile hore ho ne ho se na bopaki bo tšehetsang ho khetha levalbuterol ho feta albuterol kalafong ea asthma.
Le ha lithethefatsi tsena ka bobeli li sebetsa, lingaka li ka sekaseka ho haella ha bopaki ba bophahamo ba levalbuterol le litjeo tse phahameng ha li etsa qeto ea hore na e fuoa moriana ofe. Levalbuterol e amoheloa feela ho bakuli ba bana ba lilemo li 'ne ho ea holimo, ka hona albuterol e ka khethoa ho bana ba banyenyane. Ke ngaka ea hau feela e ka khethang meriana e nepahetseng bakeng sa boemo ba hau.
Fumana setlankane sa lengolo la ngaka
Ho bapisa le ho bapisa litšenyehelo tsa Levalbuterol vs Albuterol
Levalbuterol ke moriana oa ngaka o atisang ho koaheloa ke merero ea inshorense ea khoebo. E kanna ea koaheloa ke morero oa Medicare Part D kapa Karolo ea B ho latela hore na o fumane eng. Ntle le tšireletso, levalbuterol e ka u jella chelete e fetang $ 170. Setlankane sa SingleCare sa Levalbuterol se tloaelehileng se ka theola theko ho $ 30 li-pharmacy tse nkang karolo.
Albuterol e ka koaheloa ke morero oa Medicare Part D kapa Karolo ea B ho latela hore na o fumane eng. E boetse e koaheloa ke merero ea inshorense ea khoebo. Albuterol e ka bitsa chelete e ka bang $ 40 ntle le ho koaheloa, empa ka setlankane se tsoang ho SingleCare, o ka fumana foromo ea generic ka tlase ho $ 10 li-pharmacy tse nkang karolo.
| Levalbuterol | Albuterol | |
| E koahetsoe ka inshorense? | Ho joalo | Ho joalo |
| E koahetsoe ka tloaelo ke Medicare Part D? | Ho ipapisitse le tlhahlobo | Ho ipapisitse le tlhahlobo |
| Tekanyo e tloaelehileng | 25, 0.63 mg / 3 ml | 25, 2.5 mg, / 3 di ml |
| E tloaelehileng ea Medicare copay | Ho ipapisitse le moralo | Ho ipapisitse le moralo |
| Litsenyehelo tsa SingleCare | $ 30- $ 130 | $ 10- $ 20 |
Litla-morao tse tloaelehileng tsa Levalbuterol vs Albuterol
Le ha levalbuterol le albuterol li khetha ka mokhoa o itekanetseng bakeng sa li-beta receptors ho mesifa e batlang e boreleli ea lifofane, ho kanna ha ba le tšusumetso ea pelo ea beta-receptor e bakang keketseho ea lebelo la pelo, le tsejoang ka hore ke tachycardia. Levalbuterol le albuterol li ka baka letsoalo le ho thothomela. Migraine le botsoa li ile tsa tsejoa ka levalbuterol, empa eseng albuterol.
Sena ha se reretsoe ho ba lenane le felletseng la litlamorao tse ka bang teng. Ka kopo ikopanye le mofani oa tlhokomelo ea bophelo bakeng sa lenane le felletseng la litla-morao.
| Levalbuterol | Albuterol | |||
| Phello e lehlakoreng | E sebetsa? | Maqhubu | E sebetsa? | Maqhubu |
| Tachycardia | Ho joalo | 2.7% | Ho joalo | 2.7% |
| Migraine | Ho joalo | 2.7% | Che | Ha ho joalo |
| Dyspepsia | Ho joalo | 2.7% | Ho joalo | 1.4% |
| Mahlaba a maoto | Ho joalo | 2.7% | Ho joalo | 1.4% |
| Botsoa | Ho joalo | 2.7% | Che | Ha ho joalo |
| Hypertension | Che | Ha ho joalo | Ho joalo | 2.7% |
| Ho tšoha | Ho joalo | 9.6% | Ho joalo | 8.1% |
| Ho thothomela | Ho joalo | 6.8% | Ho joalo | 2.7% |
| Ho tšoenyeha | Ho joalo | 2.7% | Che | Ha ho joalo |
| Ho khohlela ho eketsehileng | Ho joalo | 4.1% | Ho joalo | 2.7% |
| Tšoaetso ea vaerase | Ho joalo | 12.3% | Ho joalo | 12.2% |
| Rhinitis | Ho joalo | 2.7% | Ho joalo | 6.8% |
| Sinusitis | Ho joalo | 1.4% | Ho joalo | 2.4% |
| Edema e nang le Turbine | Ho joalo | 1.4% | Che | Ha ho joalo |
Mohloli: Levalbuterol ( DailyMed Albuterol ( DailyMed )
Likamano tsa lithethefatsi tsa Levalbuterol vs Albuterol
Ka lebaka la ho tšoana ha bona ka lik'hemik'hale, litšebelisano tse ka bang teng tsa lithethefatsi bakeng sa levalbuterol le albuterol li ts'oana haholo. Azithromycin, lithibela-mafu tse tloaelehileng haholo tse atisang ho sebelisoa ho tšoaetso e phahameng ea phefumoloho, e lokela ho qojoa hammoho le levalbuterol kapa albuterol ha ho khonahala. Azithromycin, ha e sebelisoa le li-beta-agonists tse sebetsang nakoana, e na le kotsi e kholo ea ho baka ho lelefatsa QT, mofuta oa arrhythmia ea pelo. Haeba motsoako ona o tlameha ho sebelisoa, ts'ebetso ea pelo ea mokuli e lokela ho beoa leihlo haufi-ufi. Ho bohlokoa ho fumana motheo oa ts'ebetso ea pelo pele o fana ka lithethefatsi tsena ka nako e le 'ngoe.
Li-block blocker, tse atisang ho sebelisoa ho laola ho otla ha pelo le khatello ea mali, li sebetsa khahlano le li-beta-agonists. Mesebetsi ea bona e tla loantšana. Haeba mokuli a tlameha ho ba beta blocker le beta-agonist, ho sebelisoa beta blocker ea pelo. Mehlala ea li-beta blockers tsa pelo e kenyelletsa atenolol le metoprolol, hara tse ling.
Lena ha se lenane le felletseng la litšebelisano tsa lithethefatsi. Ka kopo batla boeletsi ba tsa bongaka bakeng sa kutloisiso e felletseng ea ts'ebelisano 'moho ea lithethefatsi.
| Lithethefatsi | Sehlopha sa lithethefatsi | Levalbuterol | Albuterol |
| K'hafeine | E tsoang ho Xanthine / CNS e khothatsang | Ho joalo | Ho joalo |
| Phenylephrine Pseudoephedrine | Li-decongestants | Ho joalo | Ho joalo |
| Acebutolol Atenolol Betaxolol Bisoprolol Carvedilol Metoprolol Nadolol Nebivolol Propranolol Sotalol | Beta blockers (bahanyetsi ba beta) | Ho joalo | Ho joalo |
| Amiodarone Dronedarone | Khahlano le boithabiso | Ho joalo | Ho joalo |
| Lebohang Clomipramine Nortriptyline | Tricyclic ho imeloa kelellong | Ho joalo | Ho joalo |
| Citalopram Escitalopram Fluoxetine Sertraline | Serotonin reuptake inhibitors (SSRIs) e khethiloeng | Ho joalo | Ho joalo |
| Azithromycin Clarithromycin | Lithibela-mafu | Ho joalo | Ho joalo |
| Fluconazole Itraconazole Ketoconazole | Likokoana-hloko | Ho joalo | Ho joalo |
Litemoso tsa Levalbuterol le Albuterol
Levalbuterol le albuterol li ka baka bronchospasm e makatsang, boemo boo bronchospasm kapa wheeze ea mokuli e mpefalang ho fapana le ho ntlafala. Haeba sena se etsahala, kalafo e lokela ho emisoa hanghang mme kalafo e ncha e lokela ho qalisoa.
Ho senyeha ha asma ho ka hlaha ka nako ea lihora, matsatsi kapa ho feta. Haeba mokuli oa asthmatic a qala ho hloka palo e ntseng e eketseha ea bronchodilator ho laola matšoao a asthma, sena e ka ba sesupo sa hore botsitso bo a etsahala. Bakuli ba nang le sena ba ka hloka litlhare tse khahlanong le ho ruruha joalo ka corticosteroids kapa phetoho ea meriana ea bona ea tlhokomelo.
Levalbuterol le albuterol, haholo-holo litekanyong tse kaholimo ho palo e khothalletsoang, e ka baka litlamorao tse tebileng tsa pelo le methapo joalo ka keketseho ea lebelo la pelo le khatello ea mali. Maemong a mang a tebileng, ho ts'oaroa ha pelo ho etsahetse. Le ka mohla u se ke ua feta tekanyetso e khothalletsoang eo ngaka ea hau e u laetseng eona.
Maemo a potasiamo a tlase a serum, kapa hypokalemia, a 'nile a bonoa ka levalbuterol le albuterol. Sena se ka bakoa ke ho tsukutleha ha li-intracellular. Le ha ka linako tse ling lithethefatsi tsena li sebelisoa ntle le leibole ho theola maemo a potasiamo ka boomo, phello ena e lokela ho beoa leihlo.
Lipotso tse botsoang khafetsa mabapi le Levalbuterol vs Albuterol
Levalbuterol ke eng?
Levalbuterol ke moriana oa ngaka o sebetsang ka bokhutšoane beta-agonist, o tsejoang hape e le bronchodilator. E sebelisetsoa ho phekola bronchospasm e amanang le asthma le COPD. E boetse e sebelisoa ntle le leibole ho thusa ho thibela bronchospasm e bakoang ke boikoetliso. E fumaneha ka mokhoa oa inhaler ea metered-dose inhaler hammoho le tharollo e tla sebelisoa ho nebulizer.
Albuterol ke eng?
Albuterol le eona ke sethethefatsi sa ngaka se sebelisang beta-agonist ea nakoana. E boetse e tsejoa e le bronchodilator 'me e sebelisetsoa ho phekola bronchospasm e amanang le asthma le COPD hape ho thibela bronchospasm e bakoang ke boikoetliso. E fumaneha ka mefuta e fapaneng ho kenyeletsoa matlapa a molomo, litharollo tsa molomo, li-inhalers tsa metered-dose le tharollo e tla sebelisoa ho nebulizer.
Na Levalbuterol le Albuterol li ts'oana?
Levalbuterol le albuterol li tšoana ka lik'hemik'hale, empa ha li tšoane hantle. Albuterol ke motsoako oa semorabe oa li-enantiomers tse peli tsa lik'hemik'hale, R-albuterol le S-albuterol. Ka linako tse ling ho thoe ke racemic albuterol. Levalbuterol e entsoe ka R-albuterol feela, e sebetsang haholo ka metsoako ena e 'meli.
Na Levalbuterol kapa Albuterol li betere?
Papiso ea morao-rao lithuto Ka kakaretso li bontšitse hore levalbuterol le albuterol li na le sephetho se tšoanang sa kliniki. Bangoli ba ka nka litšobotsi tse joalo ka litšenyehelo le litlamorao tse mpe ha ba khetha e 'ngoe ho e' ngoe.
Na nka sebelisa Levalbuterol kapa Albuterol ha ke le moimana?
Levalbuterol le albuterol ka bobeli ba nkoa e le mokhahlelo oa bokhachane C ke FDA. Sena se bolela hore ha ho na lithuto tse ntle tsa bongaka tse bontšang polokeho nakong ea bokhachane. Lithethefatsi tsena li lokela ho sebelisoa feela ha melemo e hlakile ho feta likotsi. Maemong ana, albuterol e kanna ea khethoa ka lebaka la boteng ba tlhaiso-leseling e ngata ea nalane mabapi le ts'ebeliso ea eona nakong ea bokhachane.
A na nka sebelisa Levalbuterol kapa Albuterol ka joala?
Ha ho na lithibelo tse tobileng le albuterol le joala. Leha ho le joalo, joala bo ka fokotsa lebelo la ho hema 'me ha ama tšebetso ea pulmonary, e leng se khahlanong le ho phekola bronchospasm.
Na Levalbuterol ke pholoso e inhaler?
E, levalbuterol HFA ke pholoso inhaler e bontšitsoeng bakeng sa ts'ebeliso ea kalafo ea ho mpefala ho matla ha asma kapa bronchospasms ka lebaka la COPD.
Na Levalbuterol ke steroid?
Levalbuterol ha se steroid kapa anti-inflammatory mme ha ea lokela ho sebelisoa sebakeng sa steroid ha ts'ebeliso ea steroid e bonts'oa, joalo ka ts'oaetso ea asthma.
Levalbuterol e nka nako e kae?
Ka karolelano, litlamorao tsa lethbuterol e le 'ngoe li ka nka lihora tse hlano ho isa ho tse tšeletseng. Levalbuterol e qala ho sebetsa metsotso e 15 kamora tsamaiso.
