Ka Sehloohong >> Thuto Ea Bophelo >> Lithibela-mafu tse 8 tse bakang C.Diff

Lithibela-mafu tse 8 tse bakang C.Diff

Lithibela-mafu tse 8 tse bakang C.DiffThuto ea Bophelo

Ho hlahisoa ha lithibela-mafu ho folisa mafu ha ho pelaelo hore ho ile ha fetola bongaka lilemong tse lekholo tse fetileng. Empa tse ling tsa lithethefatsi tsena tse makatsang, kamoo li neng li bitsoa kateng, li ka siea 'mele o le tlokotsing ea lefu le tšoaetsanoang le bitsoang C.iffiff.

C. Diff ke eng?

Clostridioides e fapane , eo pele e neng e tsejoa e le Clostridium e fapane , kapa C.Diff, ke libaktheria tse tšoaetsanoang seo se ka baka lets'ollo haholo. Matšoao a mang a tloaelehileng a C. Diff a kenyelletsa feberu, ho nyekeloa ke pelo, ho felloa ke takatso ea lijo le bohloko ba mpeng.



Ho hakanngoa hore e baka hoo e ka bang 500,000 mafu United States le Mahu a 15,000 selemo se seng le se seng, ho latela Litsi tsa Tlhokomelo le Thibelo ea Maloetse . Ha joale e arotsoe ke CDC joalo ka Tšokelo e Potlakileng - boemo ba tšokelo bo phahameng ka ho fetisisa ba Centers-ho bophelo ba motho ho tsoa ho kokoana-hloko e tšoaetsanoang ea U.S. (CDC e rera ho lokolla tlaleho e nchafalitsoeng Mabapi le data ena ea hoetla 2019.)



Ke lithibela-mafu life tse bakang C. Diff?

Joale tšebeliso ea lithibela-mafu e etsa joang hore motho a khone ho tšoaroa ke lefu le sokelang bophelo joalo ka C. Diff? Ha o nka lithibela-mafu, e sebetsa ho bolaea tšoaetso ea baktheria 'meleng oa hau. Ha e ntse e tsoela pele, lithethefatsi tsena li ka boela tsa senya libaktheria tse phetseng hantle tse bolokang bahlaseli ba kang C. Diff ba le teng. Ho bohlokoa ho hlokomela, ha se lithibela-mafu tsohle tse bakang C.Diff, mme ha se bohle ba nang le kotsi e tšoanang. Le hoja hoo e ka bang lithibela-mafu leha e le life li ka e baka, motho ea kotsi ka ho fetisisa, tabeng ena, hangata ke lithibela-mafu tse pharalletseng. Ba leng kotsing e kholo ke bakuli ba lilemo li 65 kapa ho feta ba kileng ba ba sebakeng sa tlhokomelo ea bophelo bo botle, joalo ka sepetlele kapa lehae la maqheku.

Lithibela-mafu tse pharalletseng li na le tšebetso khahlano le mefuta e mengata [e meholo] ea libaktheria tse lutseng ka maleng Dr. Hana Axelrod , motlatsi moprofesa oa bongaka Lefapheng la Mafu a tšoaetsanoang ho George Washington Sekolo sa Bongaka le Saense ea Bophelo . Ho bohlokoa haholo ho ba le baahi ba phetseng hantle le ba fapaneng ba libaktheria tsena. Ha batho ba fuoa lithibela-mafu tse pharalletseng, methapo ea bona ea mala e felile, ka tsela eo e lumella mofuta oa likokoana-hloko, joalo ka C. Diff, hore e hlahise bongata ba libaktheria tse mabifi tse hlahisang chefo e senyang mala le ho baka mafu a mabe haholo.



Erika Prouty, Pharm.D., Moprofesa oa mehleng oa motlatsi ho Koleche ea Pharmacy ea Western New England e Springfield, Massachusetts, e tsoela pele ho e senya: Lithibela-mafu tse pharalletseng li ka ba kotsi ho bakuli hobane ha li shebelle feela libaktheria tse mpe tseo re lekang ho li felisa, empa li bolaea le libaktheria tse ngata tse ntle tse ts'ebetsong ea rona ea tšilo ea lijo. .

Ka bobeli Dr. Akselrod le Dr. Prouty ba supa clindamycin le fluoroquinolones e le ba bang ba litloli tse mpe ka ho fetesisa. Lethathamo la lithibela-mafu tse e ka baka C.Diff e kenyeletsa:

  • cephalosporins
  • clindamycin ( Cleocin )
  • ciprofloxacin ( Cyprase )
  • lenaplake ( Levaquin )
  • senakepong ( Avalox , Vigamox )
  • amoxillin (Amoxil)

Ho malimabe, ho bolela Dr. Akselrod, hobane lithibela-mafu tseo li sebelisoa haholo bakeng sa ntho e 'ngoe le e' ngoe ho tloha pneumonia ho ea ho tšoaetso ea mosese. Taba e 'ngoe ke tlhokeho ea lithibela-mafu tse itseng tsa IV tse sebelisoang khafetsa ke lingaka likamoreng tsa maemo a tšohanyetso a sepetlele, le tsona tse oelang tlas'a sekhele se sephara. Lithethefatsi tsena li kenyelletsa:



  • piperacillin / tazobactam (Zosyn)
  • meropenem (Ke nka)

Likokoana-hloko tsa IV li tloaelehile maemong a ER hobane li sebelisoa e le kalafo ea mohala oa pele ha bakuli ba kula mme ba sa tsebe hantle hore na tšoaetso e bakoa ke eng, ho hlalosa Dr. Akselrod. Empa joalo ka ha setsebi sa bongaka se qoetse lefapheng lena, o tseba hantle hore na lingaka li lokela ho tsamaea ka tsela efe ka bobeli ba ho phekola bokuli, ha ba sa hlahise tšoaetso e eketsehileng. Ha nako e ntse e tsamaea re ile ra hlokomela likotsi ho fapana le melemo ea mofuta ona oa kalafo e pharalletseng, o re. E ka ba mohala o thata hore na o qala lithibela-mafu tsa IV kapa che. Se re thusang ho etsa qeto e nepahetseng ke mokhoa o bohlale le ho leka ho ba le lebaka le ikhethileng la ho fana ka lithibela-mafu.

Ke lithibela-mafu life tse sa atiseng ho baka C. Diff?

Haeba u le kotsing e kholo ea C.Diff, ho bohlokoa hore u bue le ngaka ea hau ka ho khetha kalafo e tlase. Lithibela-mafu tse ha ho bonolo hore e bake C.Diff kenyeletsa:

  • azithromycin ( Zithromax , Z-Pak )
  • tumello (Biaxin)
  • letseba ( Oracea , Vibramycin )
  • erythromycin ( E kentsoe )
  • fidaxomicin ( Bothata )
  • minocycline (Minocin, Solod )
  • metronidazole (Flagyl)

Ke lithibela-mafu life tse phekolang C. Diff?

Le ha meriana e pharaletseng e le kaholimo lethathamong la lisosa tsa C Diff, ho na le mefuta e fokolang feela ea lithibela-mafu tsa C.Diff tse khonang ho phekola tšoaetso ena. Vancomycin ke lithibela-mafu tse sebelisoang khafetsa bakeng sa C.Diff, ho bolela Dr. Prouty, a supa bohlokoa ba molomo, ho fapana le IV, kalafo: IV ha e hlile ha e kenelle tsamaisong ea mala, ka hona ha e na thuso. 'Me kaha ts'oaetso eohle e bakoa ke likokoana-hloko tse fapaneng (baktheria e bakang maloetse), ha se lithibela-mafu tsohle tse tla hlasela likokoana-hloko tseo le ho li bolaea. Ka hona, lithethefatsi tse khethehileng li tlameha ho sebelisoa kalafong ea C.Diff.



Ho 'nile ha boleloa hore sekhahla sa C.iffiff se oele lilemong tsa morao tjena bonyane ka lebaka la mananeo a botsamaisi ba lithibela-mafu lipetleleng, tse batlang ho fokotsa ho beoa ha lithibela-mafu tse sa hlokahaleng. Empa ha ho tluoa ho bakuli ba ikemiselitseng ho sebetsana le thibelo ea C.Diff, Dr. Akselrod o re ntho ea pele eo ba ka e etsang ke ho qoqa ka bolokolohi le mofani oa bona oa bongaka mabapi le hore na ba hlile ba hloka lithibela-mafu tseo, le ho fokotsa nako e sebelisitsoeng. holim'a eona.