Lovastatin vs Atorvastatin: Liphapang tse ka sehloohong le ho tšoana

Lithethefatsi Vs. Motsoalle

Lovastatin le atorvastatin ke litlhare tse tloaelehileng tse phekolang k'holeseterole e phahameng. Meriana ena ka bobeli e khetholloa e le HMG-coA reductase inhibitors. Ha e le hantle li sebetsa ka ho thibela tsela e sa tobang tlhahiso ea k'holeseterole maling. Ka ho theola k'holeseterole ea LDL, li ka thusa ho thibela kotsi ea ho hlaseloa ke pelo le stroke ho ba nang le lefu la pelo. Leha ba tšoana, ba boetse ba na le liphapang tse tla tšohloa.

Lovastatin

Lovastatin ke lebitso le tloaelehileng la Mevacor le Altoprev. E laeloa ho alafa coronary arteriosclerosis le hypercholesterolemia (cholesterol e phahameng). Ba nang le lefu la pelo ba ka phekoloa ka lovastatin ho theola li-cholesterol le LDL kaofela.

Lovastatin e fumaneha e le 10 mg, 20 mg, le 40 mg tablet. Altoprev ke lebitso la mofuta oa tokollo le hlahisitsoeng le fumanehang e le 20 mg, 40 mg, kapa 60 mg tablet. Lovastatin e khothalletsoa ho nooa le lijo tsa mantsiboea. Sena se bakoa ke ho kenella ha lovastatin ka ho ja lijo. Ba nang le mathata a liphio ba ka hloka ho noa litekanyetso tse tlase ho thibela kotsi ea litla-morao.

Atorvastatin

Atorvastatin ke lebitso le tloaelehileng bakeng sa Lipitor. E sebelisetsoa ho theola k'holeseterole e felletseng le cholesterol ea LDL ho batho ba nang le maemo a phahameng a mali. E boetse e laeloa ho fokotsa menyetla ea lefu ka lebaka la lefu la pelo le stroke.

Atorvastatin e tsamaisoa joalo ka letlapa la molomo ka matla a 10 mg, 20 mg, 40 mg, kapa 80 mg. Ho fapana le lovastatin, e ka nkoa ka nako efe kapa efe ea letsatsi. Sena se bakoa ke halofo ea bophelo ba eona. Leha ho le joalo, ha e khothalletsoe ho nkoa ka lijo. Atorvastatin le eona ha e khothalletsoe ho ba nang le lefu le bohloko la sebete.

Lovastatin vs Atorvastatin Lehlakore ka lehlakoreng la papiso

Lovastatin le atorvastatin ke meriana e 'meli ea li-statin e nang le lintho tse ngata tse tšoanang. Le ha li tšoana ka litsela tse 'maloa, li boetse li na le liphapang tsa bohlokoa. Meriana ka bobeli e ka hlahlojoa hape ka tlase.

Lovastatin	Atorvastatin
E Behetsoe Bakeng sa
Cholesterol e Phahameng Phahameng Triglycerides Thibelo ea Mafu a Pelo le Liketsahalo tse amanang le eona Matšoao a lefu la pelo Matšoao a bohloko a lefu la pelo Matšoao a lefuba	Cholesterol e Phahameng Phahameng Triglycerides Thibelo ea Mafu a Pelo le Liketsahalo tse amanang le eona Hyperlipoproteinemia Matšoafo
Kemiso ea Lithethefatsi
HMG CoA reductase inhibitors	HMG CoA reductase inhibitors
Moetsi
E tloaelehileng	E tloaelehileng
Litla-morao tse Tloaelehileng
Bohloko ba mpeng Ho sokela Bohloko bo kopaneng Ho opeloa ke hlooho Bohloko ba mesifa	Nasopharyngitis Bohloko ba mesifa Bohloko bo kopaneng Letšollo Tšoaetso ea pampiri ea moroto Bohloko ba mpeng Bohloko bo qetellong
Ho na le generic?
Lovastatin ke lebitso le tloaelehileng.	Atorvastatin ke lebitso le tloaelehileng.
Na e koahetsoe ke inshorense?
E fapana ho latela mofani oa hau	E fapana ho latela mofani oa hau
Mefuta ea litekanyo
Letlapa la molomo	Letlapa la molomo
Karolelano ea Theko ea Chelete
30 (ka matlapa a 30)	519 (ka matlapa a 30)
Theko ea Theolelo ea SingleCare
Theko ea Lovastatin	Theko ea Atorvastatin
Likamano tsa lithethefatsi
CYP3A4 inhibitors (ketoconazole, itraconazole, posaconazole, voriconazole, erythromycin, clarithromycin, HIV protease inhibitors, telaprevir, nefazodone, boceprevir, jj.) Cyclosporine Protease inhibitors (tipranavir, ritonavir, saquinavir, fosamprenavir, nelfinavir) Amiodarone Colchicine Ranolazine Fenofibrate Gemfibrozil Niacin Diltiazem Danazol Dronedarone Litlhare Lero la tholoana ea morara	CYP3A4 inhibitors (ketoconazole, itraconazole, posaconazole, voriconazole, erythromycin, clarithromycin, HIV protease inhibitors, telaprevir, nefazodone, boceprevir, jj.) Cyclosporine Protease inhibitors (tipranavir, ritonavir, saquinavir, fosamprenavir, nelfinavir) Fenofibrate Gemfibrozil Niacin Digoxin Diltiazem Dithibela pelehi Rifampin Lero la tholoana ea morara
A na nka sebelisa ha ke ntse ke rera ho ima, ke imme kapa ho anyesa?
Lovastatin e Mokhatlong oa Boimana X mme e ka baka kotsi ea lesea ha e fuoa bakhachane. Lovastatin ha e khothaletsoe ho basali ba bakhachane.	Atorvastatin e Mokhatlong oa Boimana X mme e ka baka kotsi ea lesea ha e fuoa bakhachane. Atorvastatin ha e khothaletsoe ho basali ba bakhachane.

Kakaretso

Lovastatin le atorvastatin ke meriana e sebetsang ea ho theola k'holeseterole. Ka bobeli li sebelisoa ho thibela mathata a pelo a joalo ka lefu la pelo le stroke ho bakuli ba itseng. Le ha meriana ka bobeli e sebetsa ka tsela e ts'oanang, le tsona li na le phapang ea hore na li sebelisoa joang.

Mabapi le matla, liphuputso li bontšitse hore atorvastatin e matla ho feta lovastatin. Ba nkang atorvastatin ba fumanoe ba fokotseha haholo ho LDL cholesterol. Leha ho le joalo, meriana ka bobeli e sebetsa ho fokotsa kotsi ea liketsahalo tse amanang le lefu la pelo.

Lovastatin hangata e khothalletsoa ho nooa bosiu le lijo ka lebaka la halofo ea bophelo ba eona e khuts'oane. Ka lehlakoreng le leng, atorvastatin e ka nkoa hoseng kapa bosiu.

Meriana ena ka bobeli e sebelisoa ke enzyme ea CYP3A4 sebeteng. Ka lebaka lena, ba arolelana litla-morao tse tšoanang le ho sebelisana ha lithethefatsi. Mohlala, ha lia lokela ho sebelisoa le li-inhibitors tse matla tsa enzyme ena e ka eketsang kotsi ea litla-morao.

Ts'ebeliso ea lovastatin kapa atorvastatin e lokela ho tšohloa le ngaka ea hau. Meriana ena ka bobeli ha ea lokela ho sebelisoa nakong ea bokhachane ka lebaka la kotsi ea eona ea ho lemala ha lesea. Ka lebaka la kotsi ea litla-morao le litšebelisano tse ngata tsa lithethefatsi, ho bohlokoa ho lekola ka hloko meriana ea li-statin.