Viibryd vs. Lexapro: Liphapang, ho tšoana, 'me ke hofe ho uena
Lithethefatsi Vs. MotsoalleKakaretso ea lithethefatsi le liphapang tse kholo | Maemo a phekotsoe | Tshebetso | Ho koahela inshorense le papiso ea litšenyehelo | Litla-morao | Likamano tsa lithethefatsi | Litemoso | LBH
Viibryd (vilazodone) le Lexapro (escitalopram) ke lithethefatsi tse ngolisitsoeng ka lebitso tse sebelisoang ho sebetsana le lefu le tebileng la khatello ea maikutlo (MDD). Lithethefatsi tsena ka bobeli li ka thusa ho alafa matšoao a khatello ea maikutlo, a ka kenyelletsang maikutlo a nako e telele a ho hlonama, ho felloa ke matla le ho fetoha ha boroko. Viibryd kapa Lexapro e ka laeloa kamora tlhahlobo ea bongaka ke mofani oa tlhokomelo ea bophelo ea sebetsanang le mafu a kelello.
Ka bobeli Viibryd le Lexapro ke li-anti-depressing tse sebetsang haholo ho eketsa ts'ebetso ea serotonin bokong. Serotonin ke methapo ea kutlo ea lik'hemik'hale eo ho lumeloang hore e bapala karolo ea bohlokoa maikutlong le maikutlong a boiketlo. Viibryd le Lexapro ba sebetsa e le serotonin reuptake inhibitors (SSRIs), e thusang ho eketsa maemo ohle a serotonin bokong.
Leha litlhare ka bobeli li ka sebelisoa ho phekola khatello ea maikutlo, li na le liphapang tse fapaneng tsa hore na li sebelisoa joang le hore na li sebetsa joang.
Phapang e kholo ke efe lipakeng tsa Viibryd le Lexapro?
Viibryd
Viibryd ke lebitso la vilazodone. Qalong e ile ea amoheloa ke Tsamaiso ea Lijo le Lithethefatsi (FDA) ka 2011 ho phekola lefu le leholo la khatello ea maikutlo. Hajoale ha ho na mofuta oa generic o fumanehang 'marakeng. Ntle le ho khetholloa e le SSRI, Viibryd hape ke karolo ea 5-HT1A receptor agonist.
Viibryd e tla e le 10 mg, 20 mg, le 40 mg pilisi ea molomo e nkiloeng hanngoe ka letsatsi le lijo. Viibryd e kanna ea se sebetse hantle ha e sa nkuoe le lijo. E fihla maemong a holimo maling kamora lihora tse hlano mme e na le halofo ea bophelo ba lihora tse ka bang 25 .
Lexapro
Lexapro ke lebitso la escitalopram. E ne e lumelloa ke FDA ka 2002 ho phekola MDD ho batho ba baholo le bacha ba lilemo li 12 ho isa ho tse 17. Ntle le khatello ea maikutlo, Lexapro e ka sebetsana le lefu la ho tšoenyeha le akaretsang. Mefuta ea mofuta oa Lexapro le eona ea fumaneha 'marakeng.
Lexapro e ka nkoa e le letlapa la molomo ka matla a 5 mg, 10 mg, kapa 20 mg. Hangata e nooa hanngoe ka letsatsi ka lijo kapa ntle le tsona. Lexapro e fihla sehlohlolong sa mali nakong ea lihora tse hlano mme e na le halofo ea bophelo ba ho fihlela lihora tse 32 .
| Liphapang tse kholo lipakeng tsa Viibryd le Lexapro | ||
|---|---|---|
| Viibryd | Lexapro | |
| Sehlopha sa lithethefatsi | Serotonin Reuptake Inhibitor (SSRI) e khethiloeng Karolo ea 5-HT1A agonist | Serotonin Reuptake Inhibitor (SSRI) e khethiloeng |
| Boemo ba cha / cha | Ha ho mofuta oa generic o fumanehang | Mofuta oa brand le generic oa fumaneha |
| Lebitso la generic ke mang? | Vilazodone | Escitalopram |
| Sethethefatsi se kena ka mefuta e fe? | Letlapa la molomo | Letlapa la molomo |
| Tekanyo e tloaelehileng ke efe? | 20 mg hang ka letsatsi | 20 mg hang ka letsatsi |
| Kalafo e tloaelehileng e nka nako e kae? | Nako e telele | Nako e telele |
| Ke mang ea sebelisang meriana eo? | Batho ba baholo | Batho ba baholo le bacha |
Maemo a phekoloang ke Viibryd le Lexapro
Viibryd le Lexapro ke li-anti-depressing tse amoheloang ke FDA tse sebelisetsoang ho sebetsana le lefu le leholo la khatello ea maikutlo. Sesebelisoa se seng le se seng se ka fanoa se kopane le psychotherapy le liphetoho tsa bophelo ho thusa ho fokotsa matšoao a khatello ea maikutlo.
Lexapro e boetse e lumelloa ke FDA ho sebetsana le lefu la ho tšoenyeha ka kakaretso (GAD). Le ha e sa amoheloe ka lebaka la matšoenyeho, Viibryd e ithutiloe litekong tsa bongaka bakeng sa kalafo ea matšoenyeho. Ka linako tse ling Viibryd kapa Lexapro li ka sebelisoa ntle le letšoao ho alafa boloetse bo feteletseng bo qobelloang (OCD).
| Boemo | Viibryd | Lexapro |
| Lefu le leholo la khatello ea maikutlo | Ho joalo | Ho joalo |
| Boloetse ba ho tšoenyeha ka kakaretso | Off-label | Ho joalo |
| Boloetse bo feteletseng bo qobelloang | Off-label | Off-label |
Na Viibryd kapa Lexapro e sebetsa hantle?
Tekong e le 'ngoe e sa sebetseng, ea bongaka, vilazodone le escitalopram li ne li bapisoa hlooho le hlooho har'a sampole ea bakuli ba 50. Hamilton Anxiety Scale (HAM – A) le lintlha tsa Hamilton Depression Rating Scale (HAM-D) li ile tsa theoleloa lihlopheng ka bobeli tsa kalafo. Leha ho le joalo, escitalopram e fumanoe e theola kakaretso ea HAM-A le HAM-D ho feta vilazodone (P<0.0001).
Ka tlhahlobo e hlophisitsoeng, escitalopram e ne e le ha e bapisoa le tse ling tse tšeletseng tse loantšang khatello ea maikutlo , Ho kenyeletsoa fluoxetine, citalopram le sertraline. Phuputso ena e hlahlobile litlhahlobo tse ngata tsa meta mme ea fumana hore escitalopram e sebetsa hantle ebile e fokotsa matšoao a khatello ea maikutlo kapele ho feta li-SSRI tse ling.
Ha li bapisoa le placebo, kapa ha ho na kalafo, Viibryd le Lexapro ke likhetho tse sebetsang bakeng sa ho phekola khatello ea maikutlo. Leha ho le joalo, phapang ea hore na motho o arabela joang e ka bapala karolo ea bohlokoa ho katleho ea ho imeloa kelellong. Ka hona, ho bohlokoa ho ikopanya le mofani oa tlhokomelo ea bophelo bo botle bakeng sa likeletso tsa bongaka ha u qala kapa fetohela ho e ncha ea ho imeloa kelellong .
Ho bapisa le ho bapisa litšenyehelo tsa Viibryd vs. Lexapro
Viibryd e fumaneha feela joalo ka moriana oa lebitso la lebitso. Ka lebaka lena, e kanna ea ba khetho e turang haholo ha e bapisoa le lithibela-mafu tse ling. Merero e meng ea Medicare le ea inshorense e ka koahela Viibryd. Theko ea karolelano ea chelete ea Viibryd e ka ba $ 389. Ho sebelisa setlankane sa SingleCare Viibryd ho ka theola litšenyehelo ho isa ho $ 278 li-pharmacy tse nkang karolo.
Lexapro e fumaneha e le lebitso la lebitso le meriana e tloaelehileng. Ha e bapisoa le Viibryd, ke khetho e theko e tlaase. E boetse e koahetsoe ke boholo ba Medicare le merero ea inshorense. Theko ea karolelano ea chelete ea Lexapro e tloaelehileng e ka ba $ 177. Ka setlankane sa theolelo se tsoang ho SingleCare, o ka fumana se tloaelehileng bakeng sa $ 15.
| Viibryd | Lexapro | |
| E koahetsoe ka inshorense? | Ho joalo | Ho joalo |
| E koahetsoe ka tloaelo ke Medicare Part D? | Ho joalo | Ho joalo |
| Bongata | 20 mg hang ka letsatsi (bongata ba matlapa a 30) | 20 mg hang ka letsatsi (bongata ba matlapa a 30) |
| E tloaelehileng ea Medicare copay | $ 1 - $ 11 | $ 0- $ 30 |
| Litsenyehelo tsa SingleCare | $ 278 + | $ 15 + |
Litla-morao tse tloaelehileng tsa Viibryd vs. Lexapro
Litla-morao tse atileng haholo tsa Viibryd ke letshollo, ho nyekeloa ke pelo, molomo o omileng, hlooho e opang le ho fufuleloa ho hoholo. Litla-morao tse ling tse ka bang teng li kenyelletsa ho tsekela, ho otsela, ho hlobaela le bohloko ba manonyeletso (arthralgia), hara tse ling.
Litla-morao tse atileng ka ho fetisisa tsa Lexapro ke ho nyekeloa ke pelo, hlooho, letšollo, ho fufuleloa le molomo o omileng. Litla-morao tse ling tse ka bang teng tsa Lexapro li ka kenyelletsa ho sokela le matšoao a kang a ntaramane.
Viibryd le Lexapro, joalo ka lithibela-mafu tse ling , e ka baka phetoho ea takatso ea lijo. Sena se ka lebisa ho nona kapa ho theola boima ba 'mele ho batho ba bang.
Ka bobeli Viibryd le Lexapro e ka baka litlamorao tsa thobalano . Ts'ebeliso ea khatello ea maikutlo e ka baka ho fokotseha ha thobalano (libido). Viibryd le Lexapro le tsona li ka baka ts'oaetso ea thobalano, joalo ka ho se sebetse ha erectile, le mathata a ho tsoa peo. Hobane Viibryd le eona e sebetsa joalo ka karolo ea 5-HT1A receptor agonist, e kanna ea ba le kotsi e tlase ea litla-morao tsa thobalano ho feta Lexapro.
| Viibryd | Lexapro | |||
| Phello e lehlakoreng | E sebetsa? | Maqhubu | E sebetsa? | Maqhubu |
| Letšollo | Ho joalo | 26% | Ho joalo | 8% |
| Ho sokela | Che | - | Ho joalo | 3% |
| Ho fufuleloa ho eketsehileng | Ho joalo | * | Ho joalo | 5% |
| Ho nyekeloa | Ho joalo | 22% | Ho joalo | leshome le metso e mehlano% |
| Molomo o omileng | Ho joalo | 8% | Ho joalo | 6% |
| Qoqelo | Ho joalo | tse peli% | Ho joalo | 3% |
| Matšoao a kang a feberu | Che | - | Ho joalo | 5% |
| Ho opeloa ke hlooho | Ho joalo | leshome le metso e mehlano% | Ho joalo | 24% |
| Botsoa | Ho joalo | 6% | Ho joalo | 5% |
| Ho otsela | Ho joalo | 4% | Ho joalo | 6% |
| Ho hlobaela | Ho joalo | 7% | Ho joalo | 9% |
| Liphetolelo | Ho joalo | 1% | Ho joalo | * |
| Ho eketsa takatso ea lijo | Ho joalo | 1% | Ho joalo | * |
| Boima ba 'mele | Ho joalo | 1% | Ho joalo | * |
| Ho fokotsa takatso ea lijo | Ho joalo | * | Ho joalo | 3% |
| Bohloko bo kopaneng | Ho joalo | tse peli% | Ho joalo | * |
| Ho se sebetse ha Erectile | Ho joalo | 3% | Ho joalo | 3% |
| Bothata ba ho khaola | Ho joalo | 1% | Ho joalo | 9% |
| Fokotsa libido | Ho joalo | 4% | Ho joalo | 3% |
* ha e tlalehe
Maqhubu ha a ipapise le tlhaiso-leseling e tsoang hloohong ho ea hloohong. Sena e kanna ea se be lenane le felletseng la litlamorao tse ka bang teng. Ka kopo sheba ngaka ea hau kapa mofani oa tlhokomelo ea bophelo ho ithuta haholoanyane.
Mohloli: DailyMed ( Viibryd ), Letsatsi le Letsatsi ( Lexapro )
Likamano tsa lithethefatsi tsa Viibryd vs. Lexapro
Viibryd le Lexapro li lokela ho qojoa ha ho ntse ho nkoa monoamine oxidase inhibitors (MAOIs), joalo ka selegiline le phenelzine. Viibryd kapa Lexapro ha ea lokela ho nooa nakong ea matsatsi a 14 ho tlohela MAOI kapa ho ka ba le kotsi e kholo ea lefu la serotonin. Viibryd le Lexapro le tsona li lokela ho qojoa kapa ho behoa leihlo le lithethefatsi tse ling tsa serotonergic tse kang ho imeloa kelellong, tse ka eketsang kotsi ea lefu la serotonin.
Ts'ebeliso ea Viibryd kapa Lexapro e lokela ho beoa leihlo ha o ntse o noa moriana o sa thibeleng ho ruruha (NSAID) kapa anticoagulant. Ho noa meriana ena ho ka eketsa menyetla ea ho tsoa mali.
Hobane Viibryd le Lexapro li sebelisoa haholo sebeteng, ho monyela ha tsona ho ka angoa ke lithethefatsi tse fetolang li-enzyme tse itseng tsa sebete. Li-antifungal le lithibela-mafu tse ling li ka eketsa maemo a Viibryd le Lexapro maling, a ka eketsang menyetla ea litlamorao tse mpe. Lithethefatsi tse ling tse kang li-anticonvulsants tse ling li ka fokotsa maemo a mali a Viibryd le Lexapro, a ka fokotsang katleho ea ona ka kakaretso.
Lexapro e tsejoa ka hore e ka baka tšitiso ea morethetho oa pelo e bitsoang qalo ea QT. Ho noa Lexapro ka lithethefatsi tse ling tsa antipsychotic joalo ka aripiprazole kapa quetiapine ho ka eketsa menyetla ea ho lelefatsa QT.
| Lithethefatsi | Sehlopha sa lithethefatsi | Viibryd | Lexapro |
| Selegilin Phenelzine Rasagiline | Monoamine oxidase inhibitors (MAOIs) | Ho joalo | Ho joalo |
| Paroxetine Sertraline Fluoxetine | Serotonin reuptake inhibitors (SSRIs) e khethiloeng | Ho joalo | Ho joalo |
| Venlafaxine Desvenlafaxine Duloxetine | Serotonin norepinephrine reuptake inhibitors (SNRIs) | Ho joalo | Ho joalo |
| Lebohang Clomipramine Nortriptyline | Li-anti-depressing tsa Tricyclic (TCAs) | Ho joalo | Ho joalo |
| Bupropion | Aminoketone | Ho joalo | Ho joalo |
| Buspirone | Anxiolytic | Ho joalo | Ho joalo |
| Aspirine Ibuprofen Naproxen Diclofenac | Lithethefatsi tse seng khahlanong le ho ruruha (li-NSAID) | Ho joalo | Ho joalo |
| Warfarin | Li-anticoagulants | Ho joalo | Ho joalo |
| Digoxin | Glycoside ea pelo | Ho joalo | Ho joalo |
| Sumatriptan Rizatriptan Eletriptan | Litlhapi | Ho joalo | Ho joalo |
| Ketoconazole Itraconazole | Likokoana-hloko | Ho joalo | Ho joalo |
| Ritonavir | Protease inhibitors | Ho joalo | Ho joalo |
| Clarithromycin | Lithibela-mafu | Ho joalo | Ho joalo |
| Carbamazepine Phenytoin | Li-anticonvulsants | Ho joalo | Ho joalo |
| Aripiprazole Clozapine Quetiapine | Lithibela-mafu | Che | Ho joalo |
Ikopanye le setsebi sa tlhokomelo ea bophelo bakeng sa litšebelisano tse ling tsa lithethefatsi.
Litemoso tsa Viibryd le Lexapro
Ho imeloa kelellong joaloka Viibryd kapa Lexapro ho ka eketsa menyetla ea ho ipolaea, haholoholo ho bakuli ba baholo. Ba nkang Viibryd kapa Lexapro ba lokela ho beoa leihlo bakeng sa ho mpefatsa khatello ea maikutlo le menahano ea ho ipolaea.
Selectional serotonin reuptake inhibitors (SSRIs) e na le monyetla oa ho baka lefu la serotonin, boemo bo ka bang kotsi bo hlahang ha serotonin e ngata haholo bokong. Kotsi e ea eketseha ha ho sebelisoa meriana e loantšang khatello ea maikutlo le lithethefatsi tse ling tsa serotonergic. Matšoao a lefu la serotonin a ka kenyelletsa ho otla ha pelo kapele, khatello e phahameng ea mali, ho fufuleloa, ho thothomela le feberu.
Batho ba bang ba ka hlahlojoa nalane ea lefu la ho ferekana kelellong pele ba qala kalafo le Viibryd kapa Lexapro. Li-anti-depressing tsena li na le monyetla oa ho kenya ts'ebetsong mania kapa hypomania ho batho ba bang ba nang le lefu la ho ferekana kelellong.
Viibryd le Lexapro li lokela ho thelisoa kapa ho emisoa butle ha ho hlokahala. Ho khaotsa ka tšohanyetso meriana e loantšang khatello ea maikutlo ho ka eketsa menyetla ea ho khaotsa ho tsuba.
Ikopanye le mofani oa tlhokomelo ea bophelo bakeng sa litemoso le litemoso tse ling tse ka bang teng.
Lipotso tse botsoang khafetsa ka Viibryd vs. Lexapro
Viibryd ke eng?
Viibryd ke sethethefatsi se ngolisitsoeng ka lengolo la ngaka se sebelisetsoang ho sebetsana le lefu le leholo la khatello ea maikutlo (MDD). Ke lebitso la vilazodone. Viibryd e sebetsa joalo ka serotonin reuptake inhibitor (SSRI) le karolo ea 5-HT1A receptor agonist. Hangata e nkoa e le letlapa la 20 mg hang ka letsatsi le lijo.
Lexapro ke eng?
Lexapro ke moriana o bitsoang brand-FDA o amoheloang ho sebetsana le lefu le tebileng la khatello ea maikutlo (MDD). E boetse e lumelloa ho phekola lefu la ho tšoenyeha ka kakaretso (GAD). Lebitso le tloaelehileng la Lexapro ke escitalopram. Lexapro ke sethethefatsi sa SSRI se nkiloeng hanngoe ka letsatsi.
Na Viibryd le Lexapro li ts'oana?
Viibryd le Lexapro ba sebetsa ka mekhoa e ts'oanang ho phekola maemo a bophelo bo botle ba kelello, empa ha ba tšoane. Viibryd e sebetsa joalo ka SSRI ebile e le karolo ea 5-HT1A agonist ha Lexapro e sebetsa haholoholo joalo ka SSRI. Le ha Viibryd le Lexapro ka bobeli ba lumelletsoe ho phekola khatello ea maikutlo e kholo, Lexapro le eona e lumelletsoe ho phekola matšoenyeho.
Na Viibryd kapa Lexapro li betere?
Molemo ka ho fetisisa ho imeloa kelellong ke eo u arabelang hamolemo ho eona. Viibryd le Lexapro ka bobeli ke lithethefatsi tse sebetsang tse fanoeng ke ngaka bakeng sa khatello ea maikutlo. Ha e bapisoa le Lexapro, Viibryd e ka baka litlamorao tse fokolang tsa thobalano.
Na nka sebelisa Viibryd kapa Lexapro ke le moimana?
Ho imeloa kelellong joaloka Viibryd kapa Lexapro e ka bolokeha ho nka nakong ya boimana. Leha ho le joalo, ha ho na bopaki bo lekaneng ba bongaka bo bontšang hore Viibryd kapa Lexapro ba bolokehile ka ho felletseng kapa ba kotsi ho e nka nakong ea bokhachane. Lithethefatsi tsena li lokela ho nooa feela haeba melemo e feta likotsi. Ikopanye le mofani oa tlhokomelo ea bophelo bo botle mabapi le ho noa li-anti-depressing ha u le moimana.
Na nka sebelisa Viibryd kapa Lexapro ka joala?
Ho noa ka teka-tekano ho kanna ha se ke ha baka kotsi haeba o le kalafong e sa fetoheng le Viibryd kapa Lexapro. Leha ho le joalo, tšebeliso ea joala e ka eketsa menyetla ea ho ba le litlamorao tse bohloko, joalo ka ho tsekela, ho otsela le pherekano. Ikopanye le mofani oa tlhokomelo ea bophelo bo botle mabapi le polokeho ea ho imeloa kelellong ha u ntse u noa joala.
Na Viibryd e loketse matšoenyeho?
Sesebelisoa se sebetsang Viibryd, vilazodone, se ithutiloe bakeng sa kalafo ea matšoenyeho. Ho latela liteko tsa bongaka, vilazodone e kanna ea ba khetho e sebetsang ea kalafo bakeng sa lefu la ho tšoenyeha ka kakaretso (GAD). Liphuputso tse ling lia hlokahala leha ho le joalo. Hajoale, Viibryd ha e lumelloe ke FDA ho sebetsana le matšoenyeho.
Nako e ntle ea letsatsi ea ho nka Viibryd ke efe?
Viibryd e lokela ho nooa ka nako e ts'oanang letsatsi le leng le le leng. Ho ipapisitse le karabelo ea 'mele oa hau moriana, ho ka ba molemo ho noa Viibryd hoseng kapa mantsiboea. Lingaka tse ngata li khothaletsa ho nka Viibryd hoseng ka lijo tsa hoseng.
Ho etsahalang ha nka nka Viibryd ntle le lijo?
Viibryd e kanna ea se sebetse hantle haeba e nkuoa ntle le lijo. Lebaka ke hore Viibryd e monya hamolemo ha e fuoa lijo. Ha e bapisoa le ho monngoa ha eona le lijo, ho kenella ha Viibryd ntle le lijo ho tlase ka hoo e ka bang mashome a mahlano% .
