Metoprolol tartrate vs. metoprolol succinate: Liphapang, ho tšoana, 'me ke hofe ho uena
Lithethefatsi Vs. MotsoalleKakaretso ea lithethefatsi le liphapang tse kholo | Maemo a phekotsoe | Tshebetso | Ho koahela inshorense le papiso ea litšenyehelo | Litla-morao | Likamano tsa lithethefatsi | Litemoso | LBH
Haeba u kile ua hlaseloa ke lefu la pelo kapa hajoale u phela le khatello e phahameng ea mali, ngaka ea hau e ka u fa sethethefatsi se kang metoprolol tartrate (Lopressor) kapa metoprolol succinate (Toprol XL). Le ha meriana ka bobeli e na le metsoako e tšoanang e sebetsang, e ka sebelisoa ka litsela tse fapaneng.
Bobeli ba metoprolol tartrate le metoprolol succinate ke tsa sehlopha sa lithethefatsi tse bitsoang beta blockers . Ka linako tse ling li tsejoa hape e le beta-1 selective adrenoceptor blockers le beta antagonists.
Lithethefatsi tsena li sebetsa ka ho thibela litlamorao tsa lihormone tse kang epinephrine le norepinephrine tsamaisong ea methapo e nang le kutloelo-bohloko. Tsamaiso ea methapo e nang le kutloelo-bohloko e ikarabella bakeng sa karabelo e tloaelehileng ea ho loana kapa ho fofa. Metoprolol e ka thusa ho fokotsa khatello ea maikutlo pelong, ea phomotsa methapo ea mali ho fokotsa khatello ea mali le ho kokobetsa bohloko ba sefuba.
Phapang e kholo lipakeng tsa metoprolol tartrate le metoprolol succinate ke efe?
Phapang e ka sehloohong lipakeng tsa metoprolol tartrate (metoprolol tartrate ke eng?) Le metoprolol succinate (metoprolol succinate ke eng?) E ho tsona. Metoprolol tartrate ke mofuta oa ho lokolla hanghang oa metoprolol ha metoprolol succinate e le mofuta oa tokollo e atolositsoeng. Sena se bolela hore metoprolol succinate e lokolloa ha nako e ntse e feta 'meleng e lebisang liphellong tse telele.
Metoprolol tartrate e kanna ea hloka ho nkuoa makhetlo a mangata ka letsatsi. Metoprolol succinate e ka nkuoa hang ka letsatsi hobane e nka nako e teletsana ho feta mofuta oa tartrate. Metoprolol succinate e ka sebelisoa ho bana ba lilemo li 6 le ho feta athe metoprolol tartrate e ka sebelisoa feela ho batho ba baholo.
| Phapang e kholo lipakeng tsa metoprolol tartrate le metoprolol succinate | ||
|---|---|---|
| Metoprolol Tartrate | Metoprolol Succinate | |
| Sehlopha sa lithethefatsi | Beta blocker | Beta blocker |
| Boemo ba cha / cha | Mofuta oa brand le generic oa fumaneha | Mofuta oa brand le generic oa fumaneha |
| Lebitso la lebitso ke mang? | Lopressor | Toprol XL |
| Sethethefatsi se kena ka mefuta e fe? | Letlapa la molomo | Letlapa la molomo, tokollo e atolositsoeng |
| Tekanyo e tloaelehileng ke efe? | 100 mg ho isa ho 400 mg ka letsatsi ka litekanyetso tse arotsoeng | 100 mg hang ka letsatsi |
| Kalafo e tloaelehileng e nka nako e kae? | Tšebeliso ea nako e khuts'oane kapa e telele joalo ka ha ho laetsoe ke ngaka | Tšebeliso ea nako e khuts'oane kapa e telele joalo ka ha ho laetsoe ke ngaka |
| Ke mang ea sebelisang meriana eo? | Batho ba baholo | Batho ba baholo le bana ba lilemo li 6 le ho feta |
U batla theko e ntle ka ho fetisisa ka metoprolol tartrate?
Ingolise bakeng sa litlhokomeliso tsa theko ea metoprolol tartrate 'me u fumane hore na theko e fetoha neng!
Fumana litemoso tsa theko
Maemo a tšoaroang ke metoprolol tartrate le metoprolol succinate
Mefuta ea tartrate le succinate ea metoprolol e amoheloa ke FDA ho phekola khatello e phahameng ea mali (khatello ea kelello) le bohloko ba sefuba (angina pectoris).
Metoprolol tartrate le eona e amoheloa ke FDA joalo ka kalafo hang kamora ho lefu la pelo (a hlobaetsang le myocardial infarction). Ho nka metoprolol tartrate kamora ho hlaseloa ke pelo ho ka thusa ho fokotsa kotsi ea liketsahalo tse ling tsa pelo le lefu haholo ho ba nang le lefu la methapo ea pelo. Kalafo hangata e lokela ho qala pele ho matsatsi a 3 ho isa ho a 10 kamora lefu la pelo.
Ntle le khatello e phahameng ea mali le bohloko ba sefuba, metoprolol succinate le eona e lumelloa ke FDA ho e phekola congestive pelo hloleha . Haholo-holo, metoprolol succinate e phekola bofokoli ba pelo bo sa foleng ke hore Mokhatlo oa New York Heart sehlopha sa II kapa sa III. E fanoe e le tekanyetso ea letsatsi le letsatsi, metoprolol succinate e ka ntlafatsa litholoana le ho fokotsa menyetla ea ho shoa ho bakuli ba sa sebetseng ka pelo.
Off-label Ts'ebeliso ea metoprolol e kenyelletsa supraventricular tachycardia (sekhahla se potlakileng sa pelo) le sefefo sa qoqotho (boemo bo kotsi bo bakoang ke tlhahiso e fetelletseng ea lihormone tsa qoqotho). Lits'ebeliso tse ling tse seng molaong li ka kenyelletsa kalafo ea morethetho o sa tloaelehang oa pelo (arrhythmia) le matšoenyeho a ts'ebetso .
| Boemo | Metoprolol Tartrate | Metoprolol Succinate |
| Khatello ea mali e phahameng | Ho joalo | Ho joalo |
| Bohloko bo sa foleng ba sefuba | Ho joalo | Ho joalo |
| Lefu la pelo le bohloko | Ho joalo | Off-label |
| Ho hloleha ha pelo | Off-label | Ho joalo |
| Supraventricular tachycardia | Off-label | Off-label |
| Sefefo sa qoqotho | Off-label | Off-label |
| Arrhythmia | Off-label | Off-label |
| Matšoenyeho a tshebetso | Off-label | Off-label |
Na metoprolol tartrate kapa metoprolol succinate e sebetsa hantle?
Metoprolol tartrate le metoprolol succinate ka bobeli li ts'oana ka katleho ea ho phekola khatello e phahameng ea mali le bohloko bo sa foleng ba sefuba. Leha ho le joalo, metoprolol tartrate e ka sebetsa hantle joalo ka kalafo ea lefu la pelo ha metoprolol succinate e ka sebetsa hantle joalo ka kalafo ea pelo e sa foleng.
Tleliniki liteko li bontšitse hore metoprolol tartrate e sebetsa bakeng sa khatello e phahameng ea mali le ho thibela litholoana tse bohloko kamora ho hlaseloa ke pelo. Ho fapana le moo, lithuto tse kenyeletsang nyeoe ea Merit-HF bontšitse hore metoprolol succinate e phahametse metoprolol tartrate bakeng sa ho hloleha ha pelo ho sa foleng.
Metoprolol succinate e ka fokotsa ho etela sepetlele khafetsa le lefu ka lebaka la ho hloleha ha pelo. Leha ho le joalo, setšoantšo se betliloeng , beta blocker e tloaelehileng, e kanna ea sebetsa le ho feta metoprolol succinate, ho latela teko e phatlalalitsoeng ho Lancet .
Hobane metoprolol tartrate e nkuoa makhetlo a 'maloa ho pholletsa le letsatsi, litekanyetso tsa lithethefatsi' meleng li kanna tsa se ts'oane. Sena se ka baka litla-morao tse ngata le mamello e nyane ha li bapisoa le mofuta o atolositsoeng oa tlhahiso. E le 'ngoe tlhatlhobo o fumane hore litla-morao tse kang ho otla ha pelo butle (bradycardia) li kanna tsa ba teng habonolo ka metoprolol tartrate ea hang-hang.
Ho bapisa le ho bapisa litšenyehelo tsa metoprolol tartrate vs metoprolol succinate
Metoprolol tartrate e ka rekoa e le sethethefatsi se tloaelehileng se tlamang se koaeloang ke Medicare le merero e meng ea inshorense. Ntle le inshorense, karolelano ea theko ea chelete bakeng sa generic metoprolol tartrate e ka ba $ 5. Likarete tsa litheolelo tsa SingleCare li ka sebelisoa likhemising tse nkang karolo ho fokotsa litšenyehelo tsa sethethefatsi sena. U ka fumana theko haufi le $ 4 ka setlankane sa polokelo.
Metoprolol succinate kapa extop-release metoprolol e fumaneha e le meriana e tloaelehileng e koaheloang ke boholo ba Medicare le merero ea inshorense. Metoprolol succinate e tloaelehileng e ka koaheloa ho feta lebitso la lebitso la Toprol XL. Theko e tloaelehileng ea thekiso ea Toprol XL e tloaelehileng e ka ba $ 56. Lekola pharmacy ea hau ho bona hore na o ka boloka ho feta ka karete ea ho boloka ea SingleCare. Haeba e amoheloa, u ka fokotsa litšenyehelo ho isa ho $ 9.
| Metoprolol Tartrate | Metoprolol Succinate | |
| E koahetsoe ka inshorense? | Ho joalo | Ho joalo |
| E koahetsoeng ke Medicare? | Ho joalo | Ho joalo |
| Tekanyo e tloaelehileng | Matlapa a 50 mg | Matlapa a 100 mg |
| E tloaelehileng ea Medicare copay | $ 0- $ 65 | $ 0- $ 20 |
| Litsenyehelo tsa SingleCare | $ 4 | $ 9 |
Fumana karete ea theolelo ea litlama
Litla-morao tse tloaelehileng tsa metoprolol tartrate vs metoprolol succinate
Metoprolol tartrate le metoprolol succinate li ka baka litla-morao tse tšoanang. Litla-morao tse tloaelehileng tsa metoprolol li kenyelletsa mokhathala kapa mokhathala, ho tsekela, ho tepella maikutlong, ho hema hanyane (dyspnea), le pelo e otlang butle (bradycardia). Litla-morao tse ling li kenyelletsa letšollo, ho nyekeloa ke pelo, ho hlatsa le molomo o omileng.
Liketso tsa Hypersensitivity tse kang ho phatloha kapa ho hlohlona ho ka etsahala ha ho nkuoa mofuta ofe kapa ofe oa metoprolol. E ipapisitse le Letšoao la FDA , metoprolol tartrate e ka ba le monyetla oa ho baka litla-morao tse itseng.
| Metoprolol Tartrate | Metoprolol Succinate | |||
| Litla-morao | E sebetsa? | Maqhubu | E sebetsa? | Maqhubu |
| Mokhathala | Ho joalo | 10% | Ho joalo | > 2% |
| Botsoa | Ho joalo | 10% | Ho joalo | > 2% |
| Moferefere | Ho joalo | 5% | Ho joalo | > 2% |
| Ho tepella maikutlo | Ho joalo | 5% | Ho joalo | > 2% |
| Letšollo | Ho joalo | 5% | Ho joalo | > 2% |
| Phefumoloho e khutšoanyane | Ho joalo | 3% | Ho joalo | > 2% |
| Ho otla ha pelo butle | Ho joalo | 3% | Ho joalo | > 2% |
| Molomo o omileng | Ho joalo | 1% | Ho joalo | * ha e tlalehe |
| Ho nyekeloa | Ho joalo | 1% | Ho joalo | * |
| Ho heletsa | Ho joalo | 1% | Ho joalo | * |
| Ho sokela | Ho joalo | 1% | Ho joalo | * |
Mohlomong lena ha se lenane le felletseng. Ikopanye le ngaka ea hau kapa setsebi sa meriana bakeng sa litla-morao tse ka bang teng.
Mohloli: DailyMed (metoprolol tartrate) , DailyMed (metoprolol succinate)
Likamano tsa lithethefatsi tsa metoprolol tartrate vs metoprolol succinate
Metoprolol tartrate le metoprolol succinate li ka sebelisana le meriana e mengata e tšoanang. Lithethefatsi tse ling tse nang le liketso tse tšoanang kapa tse amang metabolism ea beta blockers li ka sebelisana le mefuta ka bobeli ea metoprolol.
Metoprolol ha ea lokela ho nkoa ka lithethefatsi tse felisang catecholamine. Ho noa meriana ena ho ka eketsa litlamorao tsa beta blockers mme ha baka liketsahalo tse bohloko joalo ka khatello e tlase ea mali ( khatello ea maikutlo ) le pelo e otlang butle (bradycardia). Litholoana tse ling tse bohloko li ka kenyelletsa ho ba le botsoa le ho akheha.
Metoprolol e sebetsoa haholo ke enzyme ea CYP2D6. Ka hona, lithethefatsi tse thibelang enzyme ena li ka baka metoprolol e eketsehileng 'meleng. Ho eketseha ha metoprolol ho ka eketsa kotsi ea litlamorao.
Digoxin le lithethefatsi tse bitsoang calcium channel blockers li kanna tsa ba le litlamorao tse tlatselletsang ha li fanoa ka metoprolol. Ho noa efe kapa efe ea meriana ena ka metoprolol ho ka baka litla-morao pelong.
| Lithethefatsi | Sehlopha sa Lithethefatsi | Metoprolol Tartrate | Metoprolol Succinate |
| Tsosa maikutlo Tetrabenazine | Lithethefatsi tse felisang Catecholamine | Ho joalo | Ho joalo |
| Quinidine Fluoxetine Fluvoxamine Sertraline Bupropion Paroxetine Propafenone Haloperidol Diphenhydramine Hydroxychloroquine Terbinafine | CYP2D6 inhibitor | Ho joalo | Ho joalo |
| Digoxin | Glycoside ea pelo | Ho joalo | Ho joalo |
| Diltiazem Litlhare | Setsi sa calcium calcium blocker | Ho joalo | Ho joalo |
| Clonidine Guanethidine Betanidine | Moemeli oa alpha-adrenergic | Ho joalo | Ho joalo |
Sena e kanna ea se be lenane le felletseng la litšebelisano tsohle tsa lithethefatsi. Ikopanye le ngaka ka meriana eohle eo u ka noang ka eona.
Litemoso tsa metoprolol tartrate le metoprolol succinate
Metoprolol tartrate le metoprolol succinate ha lia lokela ho emisoa ka tšohanyetso. Haeba kalafo e nang le metoprolol e emisoa ka tšohanyetso, batho ba bang ba ka ba le kotsi e kholo ea tlhaselo ea pelo, e sa tloaelehang morethetho oa pelo , le bohloko ba sefuba. Kotsi ea liketsahalo tsena e phahame ho ba nang le lefu la pelo.
Beta blockers joalo ka metoprolol ha ea lokela ho sebelisoa ho mang kapa mang ea nang le maemo a latelang:
- Bradycardia e matla
- Pelo ea pelo e kholo ho feta degree ea pele
- Ho tšoha ha pelo
- Ho senyeha ha pelo ho fokotsehileng
- Bolwetse sinus syndrome ntle le pacemaker
- Hypersensitivity ho metsoako efe kapa efe ea lithethefatsi tsena
Ikopanye le ngaka ho bona hore na o ka ba le a mang a maemo ana pele o qala kalafo.
Beta blockers ba ka pata matšoao le hypoglycemia, kapa tsoekere e tlase maling. Ba nang le lefu la tsoekere ba ka hloka ho lekola tsoekere ea bona ea mali ha ba ntse ba nka beta blockers.
Lipotso tse botsoang khafetsa mabapi le metoprolol tartrate vs metoprolol succinate
Metoprolol tartrate ke eng?
Metoprolol tartrate ke lebitso le tloaelehileng bakeng sa Lopressor. Ke beta blocker e sebelisetsoang ho alafa khatello e phahameng ea mali le bohloko bo sa foleng ba sefuba. E boetse e amoheloa bakeng sa kalafo ea lefu la pelo le matla ho fokotsa menyetla ea ho shoa.
Metoprolol succinate ke eng?
Metoprolol succinate e boetse e tsejoa ka lebitso la lebitso la Toprol XL. Ke mofuta o fetisitsoeng oa metoprolol. Metoprolol succinate e lumelloa ho phekola khatello e phahameng ea mali, bohloko bo sa foleng ba sefuba le ho ferekana ho hloleha ha pelo .
Na metoprolol tartrate le metoprolol li succinate ka mokhoa o ts'oanang?
Che. Metoprolol tartrate ke letlapa le lokollang hanghang ha metoprolol succinate e le letlapa le lokolloang nako e telele. Li ka sebelisoa ka mekhoa e fapaneng.
Na metoprolol tartrate kapa metoprolol succinate e betere?
Metoprolol tartrate le metoprolol succinate ka bobeli li sebetsa hantle ho latela boemo ba kalafo. Metoprolol succinate e sebetsa haholo ho phekola ho hloleha ha pelo. Metoprolol succinate le eona e kanna ea ba le monyetla o monyane oa ho baka litla-morao tse ling.
A na nka sebelisa metoprolol tartrate kapa metoprolol succinate ke le moimana?
Metoprolol e lokela ho sebelisoa feela nakong ea bokhachane haeba melemo e hlakile ho feta likotsi. Ha ho liphuputso tse lekaneng tse entsoeng ho bonts'a hore meriana ena e bolokehile ka 100% nakong ea bokhachane. Ikopanye le ngaka haeba u imme kapa u anyesa.
A na nka sebelisa metoprolol tartrate kapa metoprolol succinate le joala?
Ho noa joala ha u ntse u sebelisa metoprolol ho ka eketsa menyetla ea ho otsela le ho tsekela. Ha ho khothalletsoe ka kakaretso ho sebelisa metoprolol le joala .
A na u ka fetola metoprolol tartrate ho ea succinate?
Maemong a mang, metoprolol tartrate e ka fetoloa ho metoprolol succinate. Metoprolol succinate e kanna ea khethoa bakeng sa tekanyetso ea eona ea hanngoe ka letsatsi. Ikopanye le ngaka ea hau ho fumana mekhoa ea hau ea kalafo ha u chencha meriana.
Ha ua lokela ho nka metoprolol neng?
Metoprolol ha ea lokela ho nkoa haeba u ba le lipelo tse tlase haholo, khatello e tlase ea mali kapa ho hloleha ha pelo ka matla. Ho bohlokoa ho bua ka nalane ea hau ea bongaka le ngaka ho fumana hore na o lokela ho ba metoprolol.
Ke eng eo ke lokelang ho e qoba ha ke nka metoprolol?
Joala le meriana e meng li lokela ho qojoa ha u ntse u nka metoprolol. Meriana e meng e kenyeletsang li-block block tsa calcium, ho joalo ho imeloa kelellong , 'Me tse sebetsoang ka tsela e ts'oanang le metoprolol e ka eketsa kotsi ea litlamorao tse mpe ka metoprolol.
Na metoprolol ke meriana e kotsi haholo?
Ho joalo. Metoprolol e ka nkuoa e le meriana e kotsi haholo. Ha e sebelisoa hampe, metoprolol e ka baka kotsi e kholo.
