Ka Sehloohong >> Boitsebiso Ba Lithethefatsi >> Lethathamo la ACE inhibitors: Ts'ebeliso, lihlahisoa tse tloaelehileng le tlhaiso-leseling ka polokeho

Lethathamo la ACE inhibitors: Ts'ebeliso, lihlahisoa tse tloaelehileng le tlhaiso-leseling ka polokeho

Boitsebiso ba Lithethefatsi

Angiotensin-converting enzyme (ACE) inhibitors ke sehlopha sa meriana e atisang ho sebelisoa ho phekola khatello e phahameng ea mali, kapa khatello ea mali. Ho laola khatello ea mali ho bohlokoa bakeng sa ho thibela stroke, lefu la pelo le lefu la liphio, hara mathata a mang a bophelo.

Ho fumanoa hore o na le lefu la khatello ea mali ho ka bonahala ho le boima, haholo hobane khatello ea meriana hangata ha e bontše matšoao. Mohlomong ha o tsebe hore o na le khatello ea meriana ea mali ho fihlela o etela mofani oa tlhokomelo ea bophelo. Haufi halofo ea batho ba baholo Amerika li na le khatello e phahameng ea mali, empa, ka lehlohonolo, ho na le meriana e 'maloa e fumanehang ho e laola. Sehlopha sa ACE inhibitor sa lithethefatsi ke khetho e le 'ngoe ea kalafo.

Tsoela pele ho bala ho ithuta haholoanyane ka ACE inhibitors, ts'ebeliso ea bona, le litlamorao tsa bona.

Lethathamo la ACE inhibitors
Lebitso la lebitso (lebitso le tloaelehileng)	Karolelano ea theko ea chelete	Poloko ea SingleCare	Ithute haholoanyane
Aceon (perindopril)	$ 76 ka 30, matlapa a 4 mg	Fumana litlankane tsa perindopril	Lintlha tsa Perindopril
Capoten (motsamaisi oa litšoantšo)	$ 55 ka 30, 25 matlapa a mg	Fumana litlankane tsa captopril	Lintlha tsa Captopril
Prinivil, Zestril (lisinopril)	$ 133 ka 30, matlapa a 10 mg	Fumana litlankane tsa lisinopril	Lintlha tsa Lisinopril
Vasotec (enalapril)	$ 69 ka li-30, matlapa a 10 mg	Fumana litlankane tsa enalapril	Lintlha tsa Enalapril
Lotensin (benazepril)	$ 37 ka 30, matlapa a 10 mg	Fumana litlankane tsa benazepril	Lintlha tsa Benazepril
Mavik (trandolapril)	$ 52 ka 30, matlapa a 4 mg	Fumana litlankane tsa trandolapril	Lintlha tsa Trandolapril
Monopril (fosinopril)	$ 42 ka 30, matlapa a 20 mg	Fumana litlankane tsa fosinopril	Lintlha tsa Fosinopril
Altace (ramipril)	$ 59 ka 30, matlapa a 10 mg	Fumana litlankane tsa ramipril	Lintlha tsa Ramipril
Sephetho (quinapril)	$ 58 ka 30, matlapa a 40 mg	Fumana litlankane tsa quinapril	Lintlha tsa Quinapril
Univasc (moexipril)	$ 65 ka 30, 15 matlapa a mg	Fumana litlankane tsa moexipril	Lintlha tsa Moexipril

ACE inhibitors ke eng?

ACE inhibitors ke sehlopha sa meriana e theolang khatello ea mali ka methapo le methapo e khathollang. Meriana ena e emisa tlhahiso ea hormone e bitsoang angiotensin II. Hormone ena e na le boikarabello ba ho fokotsa methapo ea hau ea mali, e ka phahamisang khatello ea mali. Ka ho phomotsa methapo ea mali le ho fokotsa khatello ea mali, ACE inhibitors e ka thusa ho eketsa phallo ea mali le ho fokotsa mojaro oa pelo. Meriana ena hangata e fuoa ba nang le khatello ea mali, ho hloleha ha pelo, mathata a liphio, lefu la tsoekere le maemo a mang a amanang le methapo ea mali le phallo ea mali.

ACE inhibitors e sebetsa joang?

ACE inhibitors e thibela enzyme e fetolang angiotensin, e fetolang angiotensin I ho angiotensin II. Angiotensin II ke hormone e matla e etsang hore mesifa e boreleli e potileng methapo ea mali e kenelle, e leng se etsang hore methapo ea mali e fokotsehe le ho phahama ha khatello ea mali.

Ha li-inhibitors tsa ACE li thibela tlhahiso ea angiotensin II, methapo ea mali e ka hola ho lumella mali ho phalla ka bolokolohi. Kalafo ka li-inhibitors tsa ACE e ka khothaletsa khatello ea mali e fokotsehileng, ea fokotsa tšenyo ho mabota a methapo ea mali, le ho ntlafatsa phallo ea mali pelong le liphio. Ho theola khatello ea mali le hona ho ka ntlafatsa ts'ebetso ea pelo ho hloleha ha pelo le ho liehisa kholo ea lefu la liphio le bakoang ke lefu la tsoekere kapa khatello ea mali.

ACE inhibitors e sebelisetsoa eng?

ACE inhibitors e sebelisoa haholo-holo ho phekola khatello e phahameng ea mali empa e kanna ea sebelisoa ho sebelisoa ho sebetsana le maemo a latelang:

Boloetse ba methapo ea mali
Ho hloleha ha pelo
Lefu la tsoekere
Lefu le sa foleng la liphio
Scleroderma
Migraine

Ho ba nang le bofokoli ba pelo, lefu la pelo, lefu la tsoekere kapa lefu le sa foleng la liphio, ACE inhibitors e nkuoa e le kalafo ea mohala oa pele oa ho fokotsa khatello ea mali kapa ho fokotsa kotsi ea mathata. ACE inhibitors le eona e na le tšireletso ea pelo e ikemetseng ka bokhoni ba bona ba ho theola khatello ea mali. Ka mantsoe a mang, lithethefatsi tsena li ka thusa ho sireletsa pelo tšenyo e bakiloeng ke khatello ea mali le lefu la pelo.

ACE inhibitors e ka kopanngoa le meriana e meng e kang diuretics kapa li-block channel tsa calcium.

Ke mang ea ka nkang li-inhibitors tsa ACE?

Batho ba baholo

ACE inhibitors hangata e sebelisoa ho phekola khatello ea mali ea batho ba baholo. ACE inhibitor ke kalafo ea mohala oa pele bakeng sa batho ba baholo ba ka tlase ho lilemo tse 60 le bao e seng Maafrika a Amerika. ACE inhibitors e tloaetse ho ba e sa sebetse hantle ho baahi ba Afrika Boroa. Batho ba baholo ba nang le lefu la tsoekere le bona ba ka fuoa ACE inhibitor ho fokotsa kotsi ea lefu la tsoekere, kapa lefu la liphio le hlahang ho ba nang le lefu la tsoekere.

Bana

ACE inhibitors e ka sebelisoa ho phekola khatello ea mali ho bana. Hape ke meriana e ratoang ho bana ba nang le lefu le sa foleng la liphio kapa lefu la tsoekere. Bana ba leloko la Afrika ba ka hloka tekanyetso e phahameng ea ho qala. Li-inhibitors tse 'maloa tsa ACE, joalo ka Lotensin le Prinivil, li bolokehile bakeng sa bana ba lilemo li 6 ho ea holimo; leha ho le joalo, mekhoa e 'maloa e boetse e bolokehile bakeng sa bana ba banyenyane. Mohlala, Capoten e ka fuoa masea, mme Vasotec e ka fuoa bana ba lilemo li khoeli le ho feta.

Batho ba baholo

Batho ba baholo ba ka nka ACE inhibitors ka mokhoa o sireletsehileng empa ba ka hloka tekanyetso e nyane ho feta batho ba baholo. Ho qala litekanyetso ho ka ba tlase mme butle-butle ho nyolohela holimo ho fihlela sephetho se lakatsehang.

Na li-inhibitors tsa ACE li bolokehile?

Ka kakaretso, li-inhibitors tsa ACE li nkuoa li bolokehile ha li na le litla-morao tse 'maloa ha li nkuoa joalo ka ha ho laetsoe. Leha ho le joalo, ho na le lihlopha tse 'maloa tsa batho tse sa lokelang ho nka li-inhibitors tsa ACE.

Batho ba nang le ho hloleha ho matla ha liphio ha baa lokela ho nka ACE inhibitors. Ts'ebetso ea liphio e tla hloka ho beoa leihlo leihlo haeba ho ne ho sebelisoa ACE inhibitor sechabeng sena. Batho ba nang le khatello ea maikutlo kamora ho nka ACE inhibitor e bakileng ho phatloha ho hoholo, ho thatafalloa ke ho hema, kapa ho ruruha ha molomo, leleme kapa molomo, le bona ba lokela ho qoba ho nka ACE inhibitor.

Lithethefatsi tse ling li ka fokotsa ts'ebetso ea li-inhibitors tsa ACE. Mohlala, ho feta tekete (OTC) lithethefatsi tse seng khahlanong le ho ruruha (li-NSAID) e ka fokotsa ts'ebetso ea li-inhibitors tsa ACE. Ho kopanya li-NSAID le ACE inhibitors ho lokela ho qojoa kapa ho beoa leihlo. Bua le mofani oa tlhokomelo ea bophelo ka meriana efe kapa efe eo u ka e nkang, joalo ka lithethefatsi tsa OTC, li-supplement le litlama pele u nka ACE inhibitor.

ACE inhibitor e hopola

Ha ho na li-ACE inhibitor tse hopolang hajoale ka Hlakubele 2021.

Lithibelo tsa ACE inhibitor

Se ke oa nka li-inhibitors tsa ACE haeba o kile oa hanyetsoa ke ACE inhibitor efe kapa efe. Haeba u kile ua ba le angioedema (ho ruruha ka tlas'a letlalo le ts'oanang le hives), u se ke ua nka ACE inhibitors.

Bakuli ba nkang Entresto (sacubitril / valsartan), sethethefatsi se nang le neprilysin inhibitor, ha baa lokela ho nka ACE inhibitor. Entresto ha ea lokela ho nkuoa nakong ea lihora tse 36 ho tloha kapa ho tloha ACE inhibitor.

Batho ba nang le aortic stenosis e matla ba sebelisang li-ACE inhibitors ba ka ba le phokotso ea pompo ea mali e hlahisang ischemia, kapa ea fokotsa phallo ea mali ho ea mesifa ea pelo.

A na u ka nka ACE inhibitors ha u le moimana kapa u anyesa?

Sehlopha sa ACE inhibitor se na le temoso ea lebokose le letšo khahlanong le ts'ebeliso nakong ea bokhachane. ACE inhibitors e ka baka kotsi le lefu ho lesea le ntseng le hola. Ho feta moo, ACE inhibitors e ka tšela lebese la matsoele mme e lokela ho qojoa ha u anyesa. Ikopanye le mofani oa tlhokomelo ea bophelo bakeng sa likhetho tsa kalafo bakeng sa khatello e phahameng ea mali pele u nka ACE inhibitor ha u le moimana kapa u anyesa.

Na ACE inhibitors e laoloa ke lintho?

Che, ACE inhibitors ha se lintho tse laoloang.

Litla-morao tse tloaelehileng tsa ACE inhibitors

Litla-morao tse tloaelehileng tsa li-inhibitors tsa ACE li kenyelletsa:

Khohlela e ommeng
Botsoa
Litekanyo tse phahameng tsa potasiamo ea mali
Khatello ea mali e tlase
Ho opeloa ke hlooho
Mokhathala
Bofokoli
Moferefere
Ho lahleheloa ke tatso

Khatello ea mali e tlase kapa likarolo tsa ho feta li ka hlaha ka litekanyetso tse 'maloa tsa pele tsa ACE inhibitors. Sena se etsahala hangata ho batho ba nang le bophahamo ba modumo ha ba qala ACE inhibitor. Ho se leka-lekane ha mokelikeli ho ka hloka ho lokisoa pele u qala ACE inhibitor.Litla-morao tse matla empa e le tse sa tloaelehang tsa ACE inhibitors li kenyelletsa:

Mathata a liphio
Liketso tse fokolang
Pancreatitis
Ho se sebetse ha sebete
Ho fokotseha ha lisele tse tšoeu tsa mali
Angioedema

Le ha e le seoelo, ACE inhibitors e ka ba le litlamorao tse mpe. Ketsahalo e le 'ngoe e bohloko ke angioedema , kapa ho ruruha ka tlasa letlalo la sefahleho kapa dikarolo tse ding tsa mmele. Ho itšoara hampe ho ACE inhibitors le hona ho teng ka seoelo empa hoa khoneha. ACE inhibitors e ka baka ho hloleha ha liphio, ka hona mofani oa tlhokomelo ea bophelo o lokela ho lekola liphio tsa hau khafetsa nakong ea kalafo.

ACE inhibitors e ka nyolla maemo a potasiamo ea mali le sesosa hyperkalemia (maemo a phahameng a potasiamo ho feta a tloaelehileng), ka hona ho lekola ho kenoa ha potasiamo ha o ntse o nka ACE inhibitor hangata hoa hlokahala. Ho nka limatlafatsi tsa potasiamo kapa ho sebelisa lintho tse nkeloang letsoai tse nang le potasiamo ha u ntse u le ho ACE inhibitor ho ka baka hyperkalemia, e ka lebisang mathateng a mang a bophelo mme e ka beha bophelo kotsing. Matšoao a ho ba le potasiamo e ngata haholo 'meleng a kenyelletsa pherekano, ho otla ha pelo ka tsela e sa tloaelehang, le ho hlohlona kapa ho ba shohlo matsohong kapa sefahlehong.

Lethathamo lena la litla-morao ha le felle. Ho bua le setsebi sa tlhokomelo ea bophelo ke tsela e molemohali ea ho fumana lenane le felletseng la litla-morao le ho fumana hore na ho nka ACE inhibitors ho loketse.

Bolella ngaka ea hau ka efe kapa efe ea tse latelang pele u nka ACE inhibitor:

Matšoao afe kapa afe a lithethefatsi
Haeba u kile ua hlaheloa ke angioedema
Haeba u na le mathata a liphio
Haeba u nkile sethethefatsi se nang le sacubitril ho sona lihora tse 36 tse fetileng
Haeba u imme kapa u anyesa

ACE inhibitors e bitsa bokae?

ACE inhibitors hangata ke meriana e theko e tlaase e fumanehang ka mabitso le mabitso a tloaelehileng. Hoo e batlang e le merero eohle ea Medicare le inshorense e tla koahela ACE inhibitors. Litšenyehelo li tla fapana ho latela moralo oa inshorense. Ntle le inshorense, theko e ka fapana haholo ho latela meriana le bongata ba matlapa a laetsoeng. Leha ho le joalo, ho sebelisa file ea Karete ea theolelo ea lengolo la ngaka Ho tsoa ho SingleCare ho ka thusa ho fokotsa litšenyehelo tsa li-inhibitors tsa ACE.