Zanaflex vs. Flexeril: Liphapang, ho tšoana, 'me ke hofe ho uena
Lithethefatsi Vs. MotsoalleKakaretso ea lithethefatsi le liphapang tse kholo | Maemo a phekotsoe | Tshebetso | Ho koahela inshorense le papiso ea litšenyehelo | Litla-morao | Likamano tsa lithethefatsi | Litemoso | LBH
Lebitso la Flexeril le khaolitsoe; leha ho le joalo, e ntse e fumaneha joalo ka generic-cyclobenzaprine-hape joalo ka mabitso a mabitso Amrix le Fexmid.
Zanaflex (tizanidine) le Flexeril (cyclobenzaprine) ke lintho tse khathollang mesifa tse sebelisetsoang ho phekola maemo a bohloko a mesifa. Haeba o ba le mathata a molala kapa a mokokotlo, o kanna oa buelloa hore mesifa e phomole joalo ka Zanaflex kapa Flexeril. Lithethefatsi tsena li ka thusa ho imolla mesifa le ho satalla ho amanang le maemo a mang a 'mele le likotsi.
Joalo ka tse ling mesifa e khathollang , Zanaflex le Flexeril ba sebetsa tsamaisong ea methapo e bohareng (CNS). Li boetse li na le litla-morao le litšenyehelo tse tšoanang. Leha ho le joalo, li na le liphapang tsa hore na li sebelisoa le ho etsoa joang.
Phapang e kholo lipakeng tsa Zanaflex le Flexeril ke efe?
Tsepiso
Zanaflex (Zanaflex ke eng?) Ke lebitso la lebitso la tizanidine mme e sebetsa joalo ka alpha-2 adrenergic agonist. Qalong e ile ea amoheloa ka 1996 bakeng sa kalafo ea ho haelloa ke mesifa. Leha ts'ebetso ea eona ea ts'ebetso e sa tsejoe, ho lumeloa hore e khona ho sebetsa ho halefa hoa mesifa ka ho thibela matšoao a methapo ea motlakase.
Zanaflex e fumaneha joalo ka letlapa la molomo ka matla a 2 mg le 4 mg. E boetse e tla joalo ka capsule ea molomo ka matla a 2 mg, 4 mg, le 6 mg. Zanaflex hangata e nkoa makhetlo a mararo ka letsatsi.
Flexeril
Flexeril (Flexeril ke eng?) Ke sethethefatsi se bitsoang FDA se amohetsoeng ka 1977. Mofuta oa Flexeril, cyclobenzaprine, o fumaneha hohle. Flexeril e tšoana hantle le li-anti-depressing tsa tricyclic mme e sebetsa haholo tsamaisong ea methapo e bohareng (CNS). E thusa ho fokotsa ts'oaetso ea mesifa ka liketso ho li-gamma- le alpha-motor system.
Cyclobenzaprine ha e sa fumaneha joalo ka Flexeril. Sebakeng seo, cyclobenzaprine e ka fumanoa tlasa mabitso a mabitso a fapaneng: Amrix (tokollo e atolositsoeng) le Fexmid (ho lokolloa hanghang). Cyclobenzaprine e lokolloang hang-hang e nkuoa makhetlo a mararo ka letsatsi ha foromo ea nako e telele e ka nkuoa hang ka letsatsi.
| Liphapang tse kholo lipakeng tsa Zanaflex le Flexeril | ||
|---|---|---|
| Tsepiso | Flexeril | |
| Sehlopha sa lithethefatsi | Boikhathollo ba mesifa | Boikhathollo ba mesifa |
| Boemo ba cha / cha | Mofuta oa brand le generic oa fumaneha | Mofuta oa brand le generic oa fumaneha Lebitso la lebitso Flexeril le emisitsoe ho la US Mabitso a mang a mabitso a kenyelletsa Amrix le Fexmid. |
| Lebitso la generic ke mang? | Tizanidine | Cyclobenzaprine |
| Sethethefatsi se kena ka mefuta e fe? | Letlapa la molomo Li-capsules tsa molomo | Letlapa la molomo Capsule ea molomo, tlhahiso e atolositsoeng |
| Tekanyo e tloaelehileng ke efe? | Tekanyo ea pele ea 2 mg, e lateloe ke litekanyetso tse latelang lihora tse 6 ho isa ho tse 8. Boholo ba litekanyetso tse 3 ka lihora tse 24. Tekanyo e ka eketsoa ka matsatsi a 1 ho isa ho a mane ka 2 mg ho isa ho 4 mg. Tekanyo e phahameng ea letsatsi le letsatsi ea 36 mg. | Matlapa a lokolloang hanghang: 5 mg ho isa ho 10 mg makhetlo a mararo ka letsatsi. Li-capsules tse lokolitsoeng nako e telele: 15 mg ho isa ho 30 mg hang ka letsatsi. |
| Kalafo e tloaelehileng e nka nako e kae? | Nako e khuts'oane kapa e telele ho latela maemo | Ha ho feta libeke tse 2 ho isa ho tse 3 |
| Ke mang ea sebelisang meriana eo? | Batho ba baholo ba lilemo li 18 ho ea holimo | Batho ba baholo le bacha ba lilemo li 15 ho ea holimo |
U batla theko e ntle ho Zanaflex?
Ingolise bakeng sa tlhokomeliso ea theko ea Zanaflex 'me u fumane hore na theko e fetoha neng!
Fumana litemoso tsa theko
Maemo a phekoloang ke Zanaflex le Flexeril
Ka bobeli Zanaflex le Flexeril ke lithethefatsi tse sebelisetsoang ho qhekella mesifa le ho kokobetsa bohloko ho tsoa maemong a mesifa. Zanaflex hangata e laeloa hore e phekole khatello ea maikutlo ho tsoa ho multiple sclerosis, cerebral palsy le ho lemala ha lesapo la mokokotlo. Flexeril hangata e laeloa ho fokotsa bohloko ba mesifa le li-spasms tse bakoang ke mathata a mokokotlo le a molala.
Zanaflex le Flexeril ka linako tse ling li laeloa hore li se ke tsa sebelisoa ho phekola fibromyalgia le migraine. Hangata e kopantsoe le lithethefatsi tse ling, Zanaflex kapa Flexeril e ka thusa ho sebetsana le ho satalla ha mesifa le ho thothomela ho amanang le ha mesifa ea mehlahare .
| Boemo | Tsepiso | Flexeril |
| Ho phatloha ha mesifa | Ho joalo | Ho joalo |
| Maemo a mesifa le mesifa | Ho joalo | Ho joalo |
| Ha mesifa ea mehlahare | Ho joalo | Ho joalo |
| Fibromyalgia | Off-label | Off-label |
| Migraine | Off-label | Off-label |
Na Zanaflex kapa Flexeril e sebetsa hantle?
Zanaflex le Flexeril ka bobeli ke lithethefatsi tse sebetsang bakeng sa mesifa le bohloko ba mesifa. Ts'ebeliso ea bona e latela hore na ke efe e loketseng maemo ka bomong. Hajoale, ha ho na data ea bongaka e bonts'a papiso e tobileng lipakeng tsa lithethefatsi tsena tse peli.
Ho latela tlhahlobo ea meta , cyclobenzaprine e ithutiloe litekong tse ngata tsa bongaka ka bopaki ba ho ts'ehetsa ts'ebeliso ea eona. Tizanidine e bontšitsoe e sebetsa hantle bakeng sa spasticity ka lebaka la multiple sclerosis. Bobeli ba cyclobenzaprine le tizanidine li fumanoe li sebetsa bakeng sa maemo a masculoskeletal joalo ka molala o bohloko kapa bohloko ba mokokotlo.
Tlhatlhobo ea meta e hlahlobile liteko tse fapaneng tse fetang 100 ha ho bapisoa le mesifa e mengata e phomolang, ho kenyeletsoa Lioresal (baclofen), Soma (carisoprodol), Robaxin (methocarbamol), Skelaxin (metaxalone), le Valium (diazepam). Ka kakaretso, phuputso e fumane hore lithethefatsi tsena li ka ts'oana ka katleho le polokeho. Litataiso tse ling li fana ka maikutlo a hore boikhathollo ba mesifa bo baka ho otsela ho eketsehileng mme e lokela ho sebelisoa nako e khuts'oane feela.
Lithethefatsi tse kang Zanaflex le Flexeril hangata li khothaletsoa hammoho le kalafo ea 'mele ho kokobetsa bohloko. Ikopanye le mofani oa tlhokomelo ea bophelo ho fumana khetho e nepahetseng ea kalafo eo u ka e sebelisang.
Ho bapisa le ho bapisa litšenyehelo tsa Zanaflex vs Flexeril
Generic Zanaflex hangata e koaheloa ke boholo ba Medicare le merero ea inshorense. Palo e behiloeng e tla fapana ho latela matla a moriana le litaelo tsa ngaka ea hau. Litsenyehelo tse tloaelehileng tsa thekiso ea Zanaflex li ka ba $ 56. Ka setlankane sa theolelo sa Zanaflex, theko ea thekiso e ka ba tlase ho $ 10 bakeng sa matlapa a 30, 4 mg.
Flexeril e boetse e koahetsoe ke boholo ba Medicare le merero ea inshorense ha e laeloa joalo ka generic. Matlapa a lokolloang hang hang a laeloa hore a nooe makhetlo a mangata ka letsatsi. Litsenyehelo tse tloaelehileng tsa thekiso ea lengolo la cyclobenzaprine li ka matha ka $ 42. U ka sebelisa monyetla oa setlankane sa Flexeril ho fumana theko e tlase ea $ 7 ka k'hemisteng e nkang karolo.
| Tsepiso | Flexeril | |
| E koahetsoe ka inshorense? | Ho joalo | Ho joalo |
| E koahetsoeng ke Medicare? | Ho joalo | Ho joalo |
| Tekanyo e tloaelehileng | 4 mg, Letlapa le leng le le leng lihora tse 6 ho isa ho tse 8 | Letlapa la 10 mg makhetlo a mararo ka letsatsi |
| E tloaelehileng ea Medicare copay | $ 0- $ 41 | $ 1- $ 35 |
| Litsenyehelo tsa SingleCare | $ 9 + | $ 7 + |
Fumana setlankane sa lengolo la ngaka
Litla-morao tse tloaelehileng tsa Zanaflex vs Flexeril
Litla-morao tse tloaelehileng tsa Zanaflex li kenyelletsa molomo o omileng, ho otsela, ho tsekela, bofokoli ba mesifa kapa mokhathala, le pipitlelano . Litla-morao tse ling tse tlalehiloeng li kenyelletsa ts'oaetso ea mosese (UTI) le motsamao o sa ithaopeng (dyskinesia).
Litla-morao tse tloaelehileng tsa Flexeril li kenyelletsa ho otsela, molomo o omileng, hlooho, mokhathala le ho tsekela. Flexeril e tsejoa hape e baka litla-morao tse ling tse kang ho sokela le ho nyekeloa ke pelo.
| Tsepiso | Flexeril | |||
| Litla-morao | E sebetsa? | Maqhubu | E sebetsa? | Maqhubu |
| Ho otsela | Ho joalo | 48% | Ho joalo | 29% |
| Molomo o omileng | Ho joalo | 49% | Ho joalo | mashome a mabeli a motso o le mong% |
| Ho opeloa ke hlooho | Che | - | Ho joalo | 5% |
| Mokhathala | Ho joalo | 41% | Ho joalo | 6% |
| Botsoa | Ho joalo | 16% | Ho joalo | 1% -3% |
| Ho nyekeloa | Che | - | Ho joalo | 1% -3% |
| Ho sokela | Ho joalo | 4% | Ho joalo | 1% -3% |
| DWS | Ho joalo | 10% | Che | - |
| Mekgatlo ya boithatelo | Ho joalo | 3% | Che | - |
Sena e kanna ea se be lenane le felletseng la litlamorao tse bohloko tse ka bang teng. Ka kopo sheba ngaka ea hau kapa mofani oa tlhokomelo ea bophelo ho ithuta haholoanyane.
Mohloli: DailyMed ( Tsepiso ), DailyMed ( Flexeril )
Likamano tsa lithethefatsi tsa Zanaflex vs Flexeril
Zanaflex e sebetsoa haholo ke enzyme ea CYP1A2 sebeteng. Lithethefatsi tse thibelang kapa tse thibelang enzyme ena li ka eketsa maemo a Zanaflex 'meleng. Maemo a eketsehileng a lithethefatsi a ka lebisa liphellong tse mpe tse kang ho otsela le ho tsekela. Zanaflex e lokela ho qojoa ka CYP1A2 inhibitors joalo ka ciprofloxacin le cimetidine hammoho le lipilisi tsa thibelo ea bokhachane tse nang le ethinyl estradiol.
Flexeril e ka sebelisana le lithethefatsi tsa serotonergic joalo ka ho imeloa kelellong le MAO inhibitors. Ho noa meriana ena ka Flexeril ho ka eketsa kotsi ea lefu la serotonin, boemo bo hlokang tlhokomelo ea bongaka hanghang.
Ka bobeli Zanaflex le Flexeril ba ka sebelisana le lithethefatsi tse nang le tsona CNS e sithabetsang maikutlo litlamorao. Mefuta ena ea lithethefatsi e kenyelletsa li-barbiturate, li-opioid le benzodiazepines. Zanaflex le Flexeril li ka ntlafatsa litlamorao tsa tsona mme tsa baka ho tsekela le ho phomola.
| Lithethefatsi | Sehlopha sa Lithethefatsi | Tsepiso | Flexeril |
| Ciprofloxacin Cimetidine Fluvoxamine Acyclovir Ticlopidine | CYP1A2 inhibitors | Ho joalo | Che |
| Ethinyl estradiol Norethindrone Levonorgestrel | Dithibela pelehi | Ho joalo | Che |
| Isocarboxazid Phenelzine Metsoako | Monoamine oxidase inhibitors (MAOIs) | Che | Ho joalo |
| Lebohang Nortriptyline Clomipramine | Tricyclic ho imeloa kelellong | Che | Ho joalo |
| Phenobarbital Pentobarbital Sekobarbital | Li-barbiturates | Ho joalo | Ho joalo |
| Oxycodone Hydrocodone Litlhapi | Li-opioids | Ho joalo | Ho joalo |
| Alprazolam Lorazepam Diazepam | Benzodiazepines | Ho joalo | Ho joalo |
* Ikopanye le setsebi sa tlhokomelo ea bophelo bakeng sa litšebelisano tse ling tsa lithethefatsi
Litemoso tsa Zanaflex le Flexeril
Zanaflex e na le monyetla oa ho baka khatello ea mali kapa khatello e tlase ea mali ka tsela e sa tloaelehang. Phello ena hangata e iponahatsa e le orthostatic hypotension se etsahalang ha motho a ya sebakeng se lokileng ka mora ho paqama. Ho feta tekano, Flexeril e tsejoa hape e baka liphetoho khatello ea mali.
Zanaflex e ka baka kotsi ea sebete ho batho ba bang, haholo-holo ba nang le nalane ea ho holofala ha sebete. Flexeril e lokela ho sebelisoa ka hloko ho batho ba nang le mathata a sebete.
Flexeril e tsejoa e baka lefu la serotonin , Haholo-holo ha e nooa ka li-anti-depressing, MAO inhibitors le li-opioid. Matšoao le matšoao a lefu la serotonin a lokela ho behwa leihlo ha o qala kalafo le Flexeril.
Lipotso tse botsoang khafetsa ka Zanaflex vs. Flexeril
Zanaflex ke eng?
Zanaflex, kapa tizanidine, ke mesifa e khathollang e sebelisetsoang ho phekola ho qepha ha mesifa ka lebaka la multiple sclerosis le kotsi ea lesapo la mokokotlo. E sebetsa ka ho thibela matšoao lipakeng tsa methapo ea motlakase ho khatholla molumo oa mesifa. Hangata e nkoa e le 2 mg kapa 4 mg tablet ka lihora tse tšeletseng ho isa ho tse robeli.
Flexeril ke eng?
Flexeril ke lebitso la cyclobenzaprine. Ke phomolo ea mesifa e bonts'itsoeng bakeng sa maemo a bohloko, a bohloko a mesifa a kang molala kapa bohloko ba mokokotlo. E sebetsa tsamaisong ea methapo e bohareng (CNS) ho kokobetsa bohloko ba mesifa le likhahla. Cyclobenzaprine e fumaneha ka mefuta ea ho lokolla hanghang le e atolositsoeng.
Na Zanaflex le Flexeril lia tšoana?
Zanaflex le Flexeril ha li tšoane. Zanaflex o na le bophelo ba halofo ea lihora tse ka bang 2,5 ha Flexeril a le halofo ea lihora tsa 18 ka karolelano. Zanaflex e kena feela matlapeng le li-capsules tsa molomo tse lokolloang hang ha Flexeril e kena ka capsule e lokolloang nako e telele.
Na Zanaflex kapa Flexeril e betere?
Zanaflex ke sethethefatsi se secha se amoheloang ke FDA bakeng sa ho halefa ha mesifa ka lebaka la multiple sclerosis le likotsi tsa mokokotlo oa mokokotlo. Flexeril ke sethethefatsi sa khale se ithutileng haholo bakeng sa bohloko ba mesifa le masapo. Sethethefatsi se betere ke sona se sebetsang hantle bakeng sa boemo ba hau bo ikhethang. Ikopanye le ngaka ho u thusa ho fumana khetho e molemohali ho uena.
Na nka sebelisa Zanaflex kapa Flexeril ha ke le moimana?
Tsepiso e ka ba kotsi ho lesea le e-so hlahe ho ea ka lithuto tsa liphoofolo. Ha ho so be le liphoofolo tse lekaneng kapa lithuto tsa batho tse bontšang hore Flexeril e kotsi ha e le moimana. Li-relaxation tsa mesifa li lokela ho sebelisoa ha feela ho na le melemo e hlakileng e fetang likotsi tse ka bang teng. Batla likeletso ho mofani oa tlhokomelo ea bophelo bakeng sa kalafo ha u le moimana.
A na nka sebelisa Zanaflex kapa Flexeril ka joala?
Ho noa joala ha o ntse o noa Zanaflex kapa Flexeril ho ka ntlafatsa litlamorao tsa lithethefatsi tsena. Hangata ha ho khothalletsoe ho noa joala ka mesifa e khathollang mesifa.
Na tizanidine e betere ho feta cyclobenzaprine?
Tizanidine e ka khethoa bakeng sa mesifa e bakoang ke multiple sclerosis, cerebral palsy le ho lemala ha lesapo la mokokotlo. Cyclobenzaprine e sebelisoa hammoho le kalafo ya mmele le ho phomola ho imolla bohloko le mesifa.
Na Zanaflex e lemalla?
Zanaflex ha se ntho e laoloang ho latela DEA. Leha ho le joalo, joalo ka tse ling tse khathollang mesifa, e ka hlekefetsoa ke batho ba bang. Zanaflex e nkuoa e le khetho ea kalafo ea nakoana. Tlhekefetso le ho itšetleha ho ka etsahala ka ts'ebeliso ea nako e telele mme ho lebisa mekhoeng e lemalloang.
Na Flexeril e thusa ka bohloko?
Flexeril ka tsela e sa tobang e kokobetsa bohloko bo amanang le likhahla tsa mesifa. Ho ipapisitse le se bakang bohloko, ngaka ea hau e kanna ea qala ho khothaletsa setlhare se rekisoang joalo ka acetaminophen kapa ibuprofen .
